Outsourced Pharma App Notes & Case Studies

  1. Optimizing And Scaling Lentiviral Vector Production 10/23/2023

    Here, we outline how the upstream and downstream workflows of the VirusExpress® platform for lentiviral vectors were optimized through the use of design of experiments and supplementary studies.

  2. Enabling Accelerated Raman Model Calibration For Real-Time Monitoring 6/14/2024

    Raman spectroscopy is a key component of a PAT strategy. Evaluate an innovative workflow designed to streamline the integration of an in-line Raman analyzer for bioreactor applications.

  3. CMO Validation As A Service 8/20/2024

    Learn about the highly successful commissioning and qualification of Wheeler's Oklahoma City CDMO facility with the overarching goal of ensuring all equipment was qualified for a Phase 3 clinical production campaign.

  4. mRNA Purification Using Anion Exchange Chromatography At Ambient Temperature 12/11/2024

    Explore how anion exchange chromatography with dual gradient elution enables efficient mRNA purification at ambient temperature.

  5. A Comparative Efficiency Analysis Of Commercial Transfection Reagents In HEK 293 Cells 3/27/2025

    This study presents a detailed comparative analysis of the efficiency, viability, and cytotoxic effects of four widely used transfection reagents on Human Embryonic Kidney 293 (HEK293) cells.

  6. Optimizing Process Loads For VHP Decontamination 2/20/2024

    Explore how CAI helped a company rescue a failing CQV project and create more efficient Vaporized Hydrogen Peroxide Material Air Lock (VHP MAL) Loads to enhance operational efficiency.

  7. Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs 5/16/2025

    By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

  8. 3D Screen Printing: Enabling A New Generation Of Complex Formulations 3/17/2025

    Screen-Printed Innovative Drug Technology can produce oral, transdermal, and implantable dosage forms while ensuring heterogeneous distribution of active ingredients.

  9. Engineering CHO K1 Cells With Three Orthogonal Transposase Systems 2/2/2024

    Transposase-mediated genome engineering enables the robust and stable relocation of discrete DNA segments (transposons) in the genome, providing a valuable tool for stable transgene expression.

  10. Development Strategies For Adenovirus-Based Gene Therapies 11/11/2024

    Scaling up viral vector production can be challenging, and ensuring consistent titers and activity requires careful optimization and technical expertise.