INSIGHTS ON CONTRACT PHARMA MANUFACTURING

  • Making The Medicine Go Down: Specialized Oral Solids Delivery Technologies

    Most oral solid formulations are designed to release the drug immediately after swallowing for rapid absorption into the bloodstream. However, some products have been developed to release the drug in a specific way following ingestion and provide a “controlled-release” of the drug products. In this article, Sandra Conway, Technical Lead at Pfizer CentreOne discusses some of the drug development technologies that provide a more specialized approach to oral dose delivery.

  • The Importance Of End-To-End Thinking During Drug Product Development

    Throughout a drug product development program it is important to build robustness and flexibility into the manufacturing process. In this article, Dr. Kashif Ghaffar, process validation pharmacist at Pfizer’s Freiburg facility, discusses what needs to be considered during product development in preparation for commercial manufacture.

  • Technology Selection For Capsule-Based Inhalation Product Development

    This webinar explores the technical issues that must be explored for successful development of effective capsule-based inhaled drug products. Key design considerations are discussed, including formulation attributes; technology selection (e.g., spray-drying, micronization); and capsule and device considerations. To learn more, please view our presentation.

  • Particle Engineering For Inhalation Drug Delivery

    Inhalation-based drug products play a critical role in addressing the rising incidence of respiratory diseases around the globe. Particle engineered-based formulations are key in designing and developing effective dry powder inhaler (DPI)-based drugs. This article discusses key parameters for choosing the right particle engineering approach to meet DPI target product profiles.

  • Engineering Approaches To Respiratory Drug Delivery: Mannitol Case Study

    Spray drying and jet milling are commercially viable engineering processes for the development of respirable drug products. This article presents a case study that explores the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol. Read our article to learn more.

CONTRACT PHARMA MANUFACTURING SOLUTIONS

  • Continuous Manufacturing Fact Sheet

    The pharmaceutical industry is facing increasing pressures on quality, pricing and productivity. The traditional batch method of manufacturing oral solid dose medications has limited scope to address these needs. Continuous manufacturing can deliver higher quality oral solid dose products, with greater flexibility and a reduced total cost of supply.

  • Patheon: Flexible And Agile Biomanufacturing Solutions

    Patheon, by Thermo Fisher Scientific, offers agility and speed to help biopharma companies stay ahead of schedule while maintaining the highest quality product. Patheon brings deep scientific expertise to every challenge and has a track record of scaling up biologics to ensure its partners gain cost and time savings at every stage of the biologic development process.

  • Lonza: CDMO Offerings Span Complete Biopharma Product Lifecycle

    Ibex Solutions, from Lonza, consist of three innovative CDMO offerings that span the complete product lifecycle of a biopharmaceutical – from preclinical to commercial stages, from drug substance to drug product, all in one location. 

  • Surfactant Analysis Services

    Successful drug product development should integrate formulation, manufacturing process, primary packaging, device and delivery to the patient. Lonza’s Drug Product Services (DPS) offering delivers a holistic approach to DP development that anticipates and prevents problems early, and ensures the result is a product that is fit for purpose.

  • Sample Fulfillment and Distribution Solutions Fact Sheet

    For over 30 years life science manufacturers have chosen Patheon, by Thermo Fisher Scientific Logistics solutions for their commercial sample distribution needs. Download the fact sheet to learn why.