DRUG DISCOVERY WHITE PAPERS & ARTICLES

  • 5 Reasons External Collaborations Fail In Drug Discovery

    In an effort to accelerate innovation, streamline the R&D process, satisfy healthcare expectations and improve the rate of return, pharmaceutical companies have come to embrace external collaborations and their outsourcing partners as an essential part of their discovery programs. This trend towards externalization is significant with roughly 90% of companies outsourcing some steps of drug discovery, and with half of all drugs now resulting from such partnerships. This white paper, discusses the different types of external collaborations research organizations engage in, the reasons that many of these partnerships fail to meet expectations, and an informatics solutions to overcome these issues.

  • Evolution Of Biologic Pipelines Calls For Next-Generation Expression Systems

    Today’s mAb competition focuses on unmet therapeutic needs and biological mechanisms that have not yet been explored. As a result of this evolution, the purification of biologics is becoming increasingly challenging. This article discusses Lonza’s XS™ expression platform, which addresses the need for next-generation expression systems.

  • From Discovery To Development: GS Expression System For Next-Generation Biologics

    Compared to traditional antibody expression, where routine purification and analytical strategies have been established over the last few years, next-generation biologics have complex designs. If you are first in class or you have a very bespoke up- and downstream process, it also means you will have bigger hurdles to overcome when it comes to regulatory support and filing. At Lonza, these challenges are addressed with the GS™ expression platform.

  • Streamlining Recombinant Protein Production

    Bringing a recombinant protein to market requires a substantial investment of time and resources, and the process is generally complex and subject to technical pitfalls.

  • Quality and Innovation Bringing Drug Discovery Back to the United States

    Outsourcing is no longer just about cost reduction. The desire for efficiency that prompted pharmaceutical and biotechnology sponsors to externalize research decades ago is now focused on services firms, which are responding by developing smarter ways of working.

  • The Road Toward Effective Translational Research

    This white paper presents the areas in translational research that have contributed to the failure of moving therapies to the clinic and the actions taken by experts to correct such deficiencies.

  • The Big Heat: What Lies Behind The Mergers, Acquisitions, And Consolidations In The Life Sciences

    In Life Sciences, last year certainly could be called the Year of the Deal. Along with 60 mergers and acquisitions (with the average deal size 49 percent larger than the previous year’s), there were three times as many initial public offerings (IPOs) in 2013 as there were the year before. These IPOs raised a cumulative $2.7 billion, which exceeded the total of the previous five years. And according to FTI Consulting’s fourth annual Life Sciences Investment Survey, investors expect these trends to continue and even grow.  By March 2014, for instance, there had already been 21 IPOs in the Life Sciences, raising an aggregate $1.3 billion.

More From Drug Discovery White Paper and Articles

DRUG DISCOVERY APPLICATIONS & STUDIES

  • True Scientific Knowledge Management In R&D: Electronic Laboratory Notebooks (ELNs)
    True Scientific Knowledge Management In R&D: Electronic Laboratory Notebooks (ELNs)

    One tool holds a unique position among R&D informatics systems. Unlike other systems, electronic laboratory notebooks (ELNs) both produce data and consume information. An ELN’s ability to capture data, observations, experiences, and context is particularly powerful when combined with other data pipelining tools. The ability to link key pieces of data and mine experiments captured in the ELN for insights fuels true scientific knowledge management. This use case describes the broad organizational benefits that BIOVIA Workbook made possible for a global pharmaceutical company, highlighting how the system is supporting efforts to gain predictive control over key processes in Research and Development.

  • Seahorse Bioscience Keeps Product Development Information In Sync With Omnify Empower
    Seahorse Bioscience Keeps Product Development Information In Sync With Omnify Empower

    Seahorse Bioscience provides analytical instruments, biomanufacturing systems, and consumable labware products for biological research and drug discovery. Seahorse technology is used to advance understanding of the role of cell metabolism in neurodegeneration, aging, cancer, cardiovascular, cell physiology, toxicology and hepatobiology, immunology, infectious diseases, mitochondrial diseases, model organisms, obesity, diabetes, metabolic disorders, screening, and translational medicine.

  • Informatics For Neglected Diseases Collaborations

    Many different public and private organizations from across the globe are collaborating on neglected diseases drug-discovery and development projects with the aim of identifying a cure for tropical infectious diseases.

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CONTRACT DRUG DISCOVERY SUPPLIERS

  • Metabolon
    Metabolon

    Metabolon, Inc. has advanced the field of metabolomics by pioneering and patenting the industry’s leading biochemical biomarker discovery and profiling platform. It has developed the technology to quickly identify and measure all of the biochemicals in a biological sample through its proprietary global processing method.

  • MPI Research
    MPI Research

    MPI Research, with global headquarters in Mattawan, Michigan, provides discovery, safety evaluation, bioanalytical, and analytical services to the biopharmaceutical, medical device, animal health, and chemical industries.

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DRUG DISCOVERY & OUTSOURCED PHARMA EVENTS

Root Cause Analysis Post ICH GCP E6 (R2): Beyond Fishbones and 5 Whys! March 27, 2017
1pm-2:30pm EDT, Online Training
Duration:  90 Minutes
Price:  $299 - Includes Bonus Handouts!
Electronic Document Management Systems (EDMS) And Electronic Common Technical Documents (eCTD) – An Overview March 28, 2017
1pm-2:30pm EDT, Online Training
Duration:  90 Minutes
Price:  $299 - Includes Bonus Handouts!
Electronic Informed Consent (eIC): How The New FDA/OHRP Final Guidance Affects You April 4, 2017
1pm-2:30pm EDT, Online Training
Duration:  90 Minutes
Price:  $299 - Includes Bonus Handouts!
Drug Development 101 – How A Drug Is Made April 5, 2017
1pm-2:30pm EDT, Online Training
Duration:  90 Minutes
Price:  $299 - Includes Bonus Handouts!
Understanding The New NIH/HHS Final Rule On Clinical Trial Reporting – Tips For Compliance Success April 6, 2017
1pm-2:30pm EDT, Online Training
Duration:  90 Minutes
Price:  $299 - Includes Bonus Handouts!