INSIGHTS ON DRUG DISCOVERY
-
The Write Side Of AI: Helping Hands, Not Replacement Plans
AI applications in medical writing are in their infancy, and the technology suffers several shortcomings including plagiarism, copyright infringement, and misinformation dissemination.
-
Bacteria Media Optimization Using In Silico Strategies
Determining ideal media composition for a bacteria is critical because it fosters a satisfactory grow rate, allowing the bacteria to reach the required growth yield.
-
The Process Of Developing Monoclonal Antibodies For Clinical Use
Explore the potential of mAbs in treating diverse conditions, from cancer to infectious diseases, and learn about their transformation from scientific breakthroughs to life-changing therapies.
-
Quality Roundtable: Optimizing Biologics Manufacturing Processes With Raw Materials
Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.
-
Leveraging Stable Pool Material To Expedite The Path To IND1/10/2024
Review the efficacy of fast stable pools in generating purified product at an early stage and learn how to accelerate the journey toward first-in-human trials and proof-of-concept studies.
-
Potent Rifampicin Derivatives Can Clear MRSA Infections At Single Low Doses When Concomitantly Dosed With Vancomycin1/4/2024
Multidrug-resistant bacteria are rendering antibiotics ineffective. Review preclinical results of a potent macrocycle derivative and why collaboration is crucial to transition discoveries into treatments.
-
The MAPPs Assay: A Useful Tool For The Assessment Of Immunogenicity1/4/2024
Explore how MAPPS demonstrates promise as a valuable tool for comprehensive immunogenicity assessment in therapeutic protein development, contributing to safer and more effective biologics.
-
The Bioanalytical Development Journey12/14/2023
Learn how a CDMO with the capability to develop assays to support a wide range of drug substances can support your journey from discovery to clinical manufacturing with reduced cost and time.
-
Considerations And Strategies For Hiring Biopharma Consultants12/8/2023
Most organizations do not have the budget or workload to justify a team spanning all possible subspecialties. So, those gaps typically are filled with consultants who add clear value to delivering products and services for the company’s clients. But how do you find the right consultants?
DRUG DISCOVERY SOLUTIONS
-
The developability evaluation comprises in silico analysis as well as a series of in vitro assays for the drug candidates, so to provide information about the integrity, purity, aggregation, thermostability, charge heterogeneity, glycosylation, poly-reactivity, potency, stability over low pH and accelerated storage conditions, and potential PKPD profile.
-
The GS Xceed® Gene Expression System is a comprehensive toolbox for development of biologics that has been used to develop not only monoclonal antibodies but also a wide variety of new molecular formats.
-
Our experience developing mammalian and microbial cell lines and our analytical capabilities enable us to identify and select clones that meet your product’s specific parameters and characteristics.
-
Lonza’s Drug Product Services delivers a holistic approach to DP development that prevents problems early and produces a product that is fit for purpose.
-
We take an agile and flexible approach with our customers programs, offering bespoke drug substance synthesis and manufacturing, helping to accelerate molecules from candidate selection to clinical proof-of-concept and onwards towards commercial scale.