Outsourced Pharma App Notes & Case Studies
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Understanding The Microfluidic Platforms For Scaling Nanoparticle Production
10/13/2022
Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.
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Implementing High Cell Density Cryopreservation In Your Seed Train
1/22/2023
Simplify seed train intensification with high cell density cryopreservation. Eliminate the need for manual scale-up steps and enable risk reduction through closed banking and inoculation processes.
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Seizing Market Share Pre-Patent Expiry: The Evolution Of A CDMO Partnership In Navigating A Paragraph IV ANDA Submission
6/26/2024
The dynamic pharmaceutical landscape demands agility and strategic foresight. Explore how leveraging a key partnership helped to overcome a looming patent expiry for a second-generation acne medication.
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Exosome Isolation By TFF And Size Exclusion Chromatography
3/6/2024
Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.
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Automated Cell Washing And Formulation In CAR T Cell Therapy Manufacturing
6/14/2024
Explore data collected from a study utilizing healthy donors in a typical CAR T cell processing workflow without a transduction step from a cross-site validation study.
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Application Of A Sf-Rhabdovirus-Negative Platform For AAV Production
3/10/2023
Discover a two-part system comprising a proven Sf-9 cell line devoid of Sf-rhabdovirus and a chemically defined medium engineered for it. Explore the performance of this medium for AAV2 production.
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AAV Full/Empty Capsid Separation Using Mechanistic Modeling
5/1/2023
In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.
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Establishing A Robust Workflow To Identify High-Performing Clones
1/13/2023
Cell line development is a complex, labor intensive, and multistep process. Learn about a platform and host cell line that minimize the risk and timeline to develop high-performing clones.
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Mammalian Bioreactors: A Characterization Data Report
12/27/2023
Review experiments that characterize the basic operating conditions of mammalian cultures in single-use bioreactors and parameters to be used when transferring cultures to/from other bioreactor systems.
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Robust Off-Gas Analyzers For High-Throughput Bioreactor Facilities
1/16/2024
Learn about an off-gas analysis system for bioreactors that can provide slightly faster response times than commercially available analyzers.