Outsourced Pharma App Notes & Case Studies

1. Streamlining Antibody Capture With Multi-Column Chromatography 3/25/2025

   Explore innovative solutions to overcome the limitations of traditional batch chromatography, improving efficiency, reducing costs, and optimizing production for complex biologics like monoclonal antibodies.

2. Virus Retention Performance Under Diverse Processing Conditions 11/14/2025

   Virus filtration is robust across a wide range of process parameters, including high protein concentration and flow decay. Discover how retention relies on size exclusion to simplify risk assessment.

3. CLD Case Study: Complex Biologics – Bispecific Fusion Nanobody 7/17/2026

   See how a bispecific fusion nanobody (BFN) achieved BsAb titers above 7 g/L with 5 of 6 clones stable beyond 60 generations — from CLD through cGMP manufacturing.

4. Lentiviral Vector Upstream Process 12/12/2025

   Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.

5. Seamless Onshoring From China-Based CDMO 11/19/2025

   How do you maintain supply continuity amid geopolitical risk? Learn how a large-scale process was requalified in just eight months to protect a clinical biologics program.

6. Specialist PV Support Transforms Safety For Orphan Medicinal Products 4/17/2026

   Learn how a UK-based company developing two orphan-designated, centrally authorized therapies successfully navigated operational challenges after transitioning from a prior provider.

7. Standardizing Cryopreservation For Cell Therapy Supply Chains 6/3/2025

   Explore how a standardized cryopreservation process is transforming leukapheresis handling by reducing risk and improving quality across the cell therapy supply chain.

8. Tank Vent Filters For Medical Water Systems 6/22/2026

   Unfiltered air exchange in water tanks can introduce contaminants. Tank vent filtration helps limit bacterial ingress, protect system integrity, and maintain consistent water quality.

9. Predicting Softgel Stability And Shelf Life Using Accelerated Modeling 7/15/2026

   Predict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.

10. Yeast Extracts: Improving Expression 4/17/2026

    Yeast extract improves E. coli protein production by over 50%, boosts desired protein attributes 4X, and offers a secure animal-free nutrient source.