Drug Discovery Whitepaper and Articles

  1. State-Of-The-Art Bispecific Antibody Development 10/11/2022

    The promise of bispecific antibodies stems from their off-the-shelf nature and ability to bind to two or more different targets or epitopes, thereby performing multiple functions.

  2. Assessing A Platform for Accelerating Product Development 3/3/2022

    Examine an innovative approach to accelerating drug development, and learn the savings to drug developers from applying the approach across the industry portfolio of investigational drugs.

  3. Adherent Versus Suspension Processes For Viral Vector Manufacturing 2/3/2022

    In adherent cell culture, cells are grown while attached to a substrate as monolayers. In suspension cell culture, cells are free-floating in the culture medium. Which offers more benefits?

  4. Formulation Development Strategy For Early Phase Human Studies 1/27/2022

    Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.

  5. Testing Cell Line Development Technology Platforms In Parallel 1/18/2022

    Access to multiple cell line development platforms — and the option to test them against one another — can minimize project risk, optimize titers, and differentiate vendor partners.

  6. Automated Bag Thawing System For CAR-T Cell Therapy Manufacturing 1/11/2022

    The performance of the VIA Thaw CB1000 is compared to thawing in a water bath. The VIA Thaw™ dry thawing system shows comparable performance to a water bath with less handling.

  7. Crystallization Of Challenging Pharmaceutical Targets To Aid Drug Discovery 12/13/2021

    Discover a few successful strategies used when growing crystals of challenging pharmaceutical targets to aid drug discovery and two case studies performed by an experienced team of crystallographers.

  8. Streamlining Upstream Plasmid DNA Manufacturing 12/9/2021

    Here we will discuss the scalable process workflow solutions available from initial R&D investment to clinical testing and commercialization.

  9. Raman vs. MIR Spectroscopy For Mammalian Cell Culture Monitoring 12/9/2021

    A direct comparison between the two technologies was conducted to investigate which system is more suitable for analyzing mammalian cell culture(s).

  10. Process Development For AAV Vector Production In Suspension Cells 11/19/2021

    Review experiments for the adaptation of the HEK293 suspension cell line for transient transfection and scalable adeno-associated virus (AAV) production.