SMALL MOLECULE OUTSOURCING
Cambrex Scientist Spotlight: Shawn Conway
Shawn Conway, Senior Director of Operations in High Point, NC, leads a dynamic team of engineers and chemists at Cambrex, focused on supporting clients throughout the entire product life cycle.
Scaling Up A Revolutionary Amorphous Solid Dispersion Platform
Process parameter and quality attribute relationships, including those for typical pre- and post-ASD unit operations, will be explored in the context of real-world examples.
Fostering A Collaborative, Cross-Functional Approach
Our collaborative environment ensures efficient project execution and thorough product testing across multiple sites, consistently delivering client satisfaction.
Accelerating Clinical Development: Modern Tools In Process Chemistry
Whether you aim to address bottlenecks or explore advanced techniques, gain a practical and forward-thinking perspective to streamline early-phase development with HTE and model-based approaches.
Sustainability By Design In API Manufacturing
Explore the urgent need for sustainability in small molecule API manufacturing, as well as reveal regulatory drivers, green chemistry innovations, and practical strategies to reduce emissions.
ADHD Awareness: How This Novel Technology Can Guide The Way
Explore Nanoform's innovative nanoparticle technology and the value it can bring to molecules in development or products on the market for neurological disorders such as ADHD.
Solid Formulation: Spray Drying Process
Transform your pharmaceutical development with an innovative spray drying technology that enhances API solubility to improve drug bioavailability and formulation performance.
The Paradigm Shift To Continuous Flow Processes: A Holistic View
A clear increase in continuous flow processes has emerged over the past decade, thanks to the commercialization of preparative flow reactor units.
Cambrex Scientist Spotlight: Ross McLellan
Ross McLellan, Team Lead for Solid Form Screening in Edinburgh, UK, leads a team dedicated to complex solid form screening and materials characterization for Cambrex’s global client base.
Building Better Degraders: Targeted Protein Degradation Partners
Learn from industry experts about the latest advances in chemical building blocks for protein degradation, including warheads, linkers, and ligands, and their role in constructing superior degrades.
Chromatography, Purification & Isolation Technologies
Explore options for the field of chromatography and allied downstream technologies and how these technologies are applied to design favorable processes in order to generate true customer benefit.
Rapid, Material-Sparing Feasibility Screening For Hot Melt Extrusion
Discover a screening process to quickly assess HME feasibility that yields more accurate predictions for API loading and degradation while saving material and time compared to traditional approaches.
3D Screen Printing: Breakthrough Solutions For Patient-Centric Therapies
Explore 3D screen printing’s potential to revolutionize pharmaceutical manufacturing with scalable, customizable, multi-drug tablets and precise, patient-centric drug release profiles.
A Data-Driven Approach To Container Closure Integrity
Gain confidence in your container closure system selection by utilizing a stepwise and data-driven approach to predicting and verifying container closure integrity.
Analytical Reference Materials For The Pharma Industry
Reference materials are critical for manufacturers to ensure safe and efficient drug material production. Discover a partner that provides high-quality analytical tools to meet your process needs.
Dramatic Reduction Of Solvent Usage In Pharmaceutical Spray Drying
Using volatile processing aids to increase drug solubility in more environmentally friendly solvents, like methanol, reduces the amount of solvent required to manufacture amorphous solid dispersions (ASDs).
AI Based Screening And Selection Of Co-Formers For Co-Crystallization
Explore how AI and quantum chemistry are accelerating co-crystal screening and solving solubility challenges in drug development, as well as key technical considerations for identifying optimal co-formers.
How Can Nanoparticle Engineering Make The Difference For Alzheimer's?
Commercial Insights Officer Jamie Unwin discusses the power of innovative nanoparticle engineering technology and AI-based digital twin.
Patient- And Planet-Centric Bioavailability And Sustained Delivery
By reducing the size of drug particles, nanoforming offers new opportunities — from increased bioavailability to sustained drug delivery. Discover the potential benefits supported by case studies.
Improving Bioavailability, Drug Loads, And Pill Burdens Of Solid Dispersions
Explore the pros and cons of marketed amorphous solid dispersions with so-far unpublished data as well as a green alternative to ASDs: best-in-class nanotechnology to manufacture nanocrystals.
Continuous Flow Techniques For Fine Chemical Manufacturing
Explore the advantages and challenges of continuous flow processes and the concept of mini-monoplant technology, along with examples that demonstrate the versatility of continuous processing.
Delivering Commercial Success: Large-Scale API Production Services
Watch to see how one company excels in overcoming the most challenging small molecule API synthesis obstacles to help propel your program to new heights, regardless of the batch size.
Your Journey To GMP With Emphasis On Linker Payload Development
Develop lower-risk conjugation strategies by incorporating the critical insights we highlight in our review of semi-synthetic versus synthetic linker–payloads and their respective advantages and limitations.
New Approaches To Tailored Release Profiles
Tailored drug release is evolving from formulation tactic to precision therapy strategy, optimizing timing, site, and rate of delivery for improved patient outcomes.
Cambrex Scientist Spotlight: Elena Bejan
Holding a Ph.D. in organic chemistry from Paris-Sud University and an MBA from the Rotman School of Management, Bejan leads R&D efforts at Cambrex with a focus on scientific innovation.
How To Design An HPAPI Plant And Its Containment Systems
Dr. Friederike Hermann, head of occupational hygiene and biosafety, shares her expertise on requirements and evaluating the right containment that meets the needs of all process steps and stakeholders.
Challenges Of Moving A Bioconjugate Candidate From Clinic To Market
Drug developers must successfully navigate the path to market, under the growing pressure of regulation and competition, and while carefully managing technical and financial risk.
Cambrex Scientist Spotlight: Luigi Bellone
Luigi Bellone, Head of Quality Assurance in Paullo, Milan, brings over 20 years of experience in quality assurance (QA), quality control (QC), and regulatory compliance within the pharmaceutical industry.
Improve The Performance Of Your Small And Large Molecule Medicines
Explore the latest in nanotechnology advancements including recent clinical data, formulation applications, and API optimization to NanoImprove formulations.
The Fusion-Based, Solvent-Free Process Disrupting Spray Drying
Review a commercially-ready process capable of reproducing spray-dried dispersions with less manufacturing complexity and environmental impact, and out-designing and outperforming spray drying.
Combination Products: Navigating Regulatory Strategy, Design Verification
Delve into the intricacies of combination products and the regulatory expectations, including risk-based determination, evaluation, and documentation approaches for performance requirements.
Taste Masking 101: Sensory And Performance Evaluation
Learn how techniques and innovations in taste masking sensory and performance evaluation can help accelerate your formulation development and confirm desired taste profile.
Strategic CMC Planning Through A Phase-Appropriate Quality Approach
A phase-appropriate quality approach ensures quality activities align with the unique risks and challenges of each development stage. Watch to learn how to apply such an approach to chemistry, manufacturing, and controls planning.
Challenges With Pediatric Flavors For Taste Enhancement And Modulation
Taste masking for children can present unique challenges for drug developers. Learn how we can use flavor, not just to provide a desired taste, but also to provide taste masking.
Solvent-Free, Fusion-Based Amorphic Dispersion Process
Discover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
Calcium Carbonate As TiO2 Alternative In Coating
Explore how calcium carbonate can replace titanium dioxide in tablet coating, as well as learn formulation strategies and review color performance data to support high-quality finishes in applications.