OP White Papers - random

  1. SEDDS: Improving Oral Bioavailability Of Poorly Soluble Compounds 8/20/2026

    Nearly 90% of marketed drugs have poor water solubility. Learn how self-emulsifying drug delivery systems (SEDDS) resolve oral bioavailability failures across BCS Class II and IV compounds.

  2. Innovations In API Manufacturing Of Small Molecule Drugs 5/6/2026

    Read how advances in people, processes, technology, materials, analytics, and sustainability are reshaping small‑molecule API manufacturing to reduce costs, scale efficiently, and meet future demand.

  3. Achieving Rapid, High-Titer Expression For Next-Generation Biologics 3/5/2025

    This advanced cell line development technology overcomes production challenges related to the expression and scalability of complex biologics.

  4. Choosing The Best Amorphous Dispersion Path Before It Costs You 6/22/2026

    Parallel screening across multiple solid dispersion platforms early optimizes drug solubility and stability, building a strong technical foundation that prevents costly development delays.

  5. (Cross-) Contamination Control Through Effective Equipment Cleaning 5/6/2026

    Discover science-driven cleaning strategies that reduce cross-contamination, enable safe multiproduct manufacturing, and support faster, flexible GMP changeovers.

  6. 5 Steps To Design A Microbiological Performance Qualification For Facilities 4/21/2025

    Explore five steps to design an EMPQ for sterile manufacturing: classification, protocol drafting, cleaning evaluation, disinfectant efficacy testing, and continuous improvement.

  7. Open-Label Study Assessing Relative And Absolute Bioavailability 1/26/2026

    Consistent absorption across different formulations and dietary conditions ensures stable therapeutic exposure. This flexibility simplifies patient dosing schedules and supports manufacturing transitions.

  8. Digital Innovation In Pharmacovigilance 10/1/2024

    Explore how AI can transform your pharmacovigilance efforts and enhance patient safety by leveraging the insights and decision framework outlined here.

  9. Life Cycle Assessment Of Extended Use Strategies For Single-Use Assemblies 4/17/2026

    Examine how extending the use of single‑use assemblies can significantly reduce emissions, resource consumption, and waste in bioprocessing, offering a data‑backed path toward sustainability.

  10. The Problem With Construction Quality 10/21/2024

    Data center construction quality management is inadequate, with issues traced to human error. A stronger focus on quality control and assurance is needed for success.