OP White Papers - random

  1. The Importance Of Quality In Raw Material Selection 1/16/2025

    Learn how to select high-quality raw materials for cell-based manufacturing in this exploration of the criticality of raw materials, from preclinical development to commercialization. 

  2. Transformative Innovation: Advancing Drug Development Using In Silico Modeling 3/4/2026

    Explore how predictive modeling and in silico strategies can turn complex data into actionable insights that accelerate drug development and reduce risk across the development lifecycle.

  3. Developing Pulmonary Dosage Forms For Complex Molecule Delivery 9/23/2025

    Discover how next-generation inhalation technologies can transform pulmonary drug delivery and unlock new therapeutic possibilities for a wide range of respiratory diseases.

  4. ADC Manufacturing: Practices, Challenges, And The Road Ahead 6/15/2026

    ADCs are advancing quickly, but manufacturing complexity is rising just as fast. Key challenges in scale-up, regulation, and costs are reshaping how the next generation of therapies will be delivered.

  5. Sample-Attribute-Based Selection Strategies For AAV %Full Determination 10/2/2026

    AAV %Full analysis must distinguish full, empty, and partial capsids, with complementary methods selected according to sample characteristics, analytical needs, development stage, and context.

  6. Selecting A CDMO For Custom Activated PEGs 1/27/2026

    Custom-activated PEGs require thoughtful planning and precise analytical control. Discover key considerations for selecting a partner capable of supporting scalable, compliant PEGylation.

  7. Addressing Plasmid DNA Challenges In Large-Scale AAV And Lentivirus Manufacturing Using dbDNA 9/21/2026

    Plasmid DNA supply and regulatory concerns constrain large-scale viral vector manufacturing. Here, we examine whether enzymatically generated dbDNA can deliver comparable rAAV and rLV production outcomes.

  8. How The Accelerator™ Drug Development Model Enhances eNPV 2/25/2026

    Discover how an integrated CDMO and CRO model can accelerate development timelines, add up to $62.9 million in value, and help you maximize long-term pipeline success with a single, streamlined partner.

  9. A Scalable Platform To Revolutionize Gene Therapy Manufacturing 11/22/2024

    Discover how our innovative rAAV production platform can revolutionize your gene therapy pipeline with unparalleled yield, quality, and scalability.

  10. The Case For Non-Viral Circular Single-Stranded HDR Donors 8/13/2026

    Enable efficient, low-toxicity genome editing without viral vectors. This cell-free circular ssDNA platform preserves stem cell fitness while supporting scalable manufacturing.