Insights On Drug Discovery
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Navigating The Small Molecule CMC Pathway
1/19/2023
Advancing a small molecule candidate from discovery to clinic is a complicated journey. Learn more about the factors that can accelerate timelines and help improve downstream clinical outcomes.
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Validated HPLC-UV Method For Quantification Of Paxalisib
1/18/2023
Examine research into the development and validation of a HPLC method for the quantitation of paxalisib in mouse plasma and its potential use for routine therapeutic drug monitoring.
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Spotlight On Discovery Biology With Dr. Jayashree Aiyar
11/28/2022
Dr. Jayashree Aiyar, VP and Head of Discovery Biology, highlights key research areas for global pharma and biotechs, including exciting projects spanning PROTACs, cell and gene therapy, omics, and more.
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Validated LC–MS/MS Method For The Determination Of Copanlisib
11/14/2022
Review study findings on a validated LC–MS/MS method for quantifying copanlisib from a mouse dried blood spot and its potential for enabling desirable sensitivity, accuracy, and precision.
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How To Leverage Modeling And Simulation In The Candidate Development Stage
10/27/2022
Modeling and simulation provides another way to predict the clinical performance of a molecule, based on a robust and holistic approach, before investing the required time and money.
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State-Of-The-Art Bispecific Antibody Development
10/11/2022
The promise of bispecific antibodies stems from their off-the-shelf nature and ability to bind to two or more different targets or epitopes, thereby performing multiple functions.
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Relying On Nonclinical Development Basics For Your Program
8/8/2022
Enhance the ability to assemble the right experts to implement the best strategy when determining which nonclinical studies are necessary for a program.
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Improving The Enrichment Of Mononuclear Cells For CAR T Cell Therapies: The Importance Of Platelet Depletion
7/26/2022
Explore why, how, and when you should carry out platelet depletion to achieve successful T cell enrichment.
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Biopharmaceutics In Early Drug Development - Overcoming Challenges For Small Molecules
7/19/2022
Chris Roe, Principal Research Fellow at Quotient Sciences, discusses effective strategies to overcome biopharmaceutic challenges for small molecules in today’s drug development pipeline.
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Analytical Prowess Powers Efficient CLD Through Data-Driven Decision-Making
7/12/2022
Trustworthy analytics enable the flexibility and responsiveness to proceed where the data indicates, pushing clones or cells closer, at each step of CLD, to an environment conducive to a product’s intended quality specifications.