Insights On Drug Discovery

  1. Phenotypic Characterization Of Bleomycin-Induced Pulmonary Fibrosis Mod 9/8/2025

    To gain deeper biological insight, lung injury in this model has been further characterized through cellular phenotyping, gene expression analysis, and cytokine profiling.

  2. Decoding The Conformational Plasticity Of Ternary Complexes For Protacs' Differential Activity 9/8/2025

    Leverage our insights into PROTAC ternary complex plasticity and stability to accelerate the design of next-generation therapeutics.

  3. Scalable Production Of High-Purity Nanobodies Using Yeast Expression System 9/8/2025

    Leverage scalable K. pastoris expression systems to produce high-quality nanobodies for cutting-edge therapeutic, diagnostic, and research applications.

  4. Streptozotocin-Induced Diabetic Peripheral Neuropathic Pain Model 9/8/2025

    Emerging research highlights that insulin deficiency drives sensory neuropathy, and early insulin therapy may help prevent or alleviate chronic diabetic neuropathic pain.

  5. NIH:OVCAR-3 Human Ovarian Cancer Model 8/26/2025

    Review studies using the NIH:OVCAR-3 model of human ovarian cancer in the subcutaneous setting in NSG mice with multiple standard agents and vehicles. This model has shown reproducible growth.

  6. An Alternative Genetic Engineering Tool In CHO Cells 8/15/2025

    Discover how transposon technology is being reimagined as a precise genetic engineering tool to create high-performing CHO cell lines for biotherapeutic production with enhanced metabolic and glycan profiles.

  7. Designing IND-Enabling Toxicity Studies For Complex Drug Modalities 8/6/2025

    Traditional toxicity studies don’t always fit today’s complex drug modalities. Watch as experts discuss how we’re adapting small molecule IND-enabling studies to meet modern therapeutic challenges.

  8. Discovery Studies: An Agile Approach To Early Data For Quicker Decisions 8/6/2025

    Discover the power of discovery research, key trends shaping early-phase drug development, and two exclusive case studies from our Sacramento facility.

  9. Random And Semi-Targeted Integration In Cell Line Development 8/5/2025

    While semi-targeted approaches may offer precision, uncover how they may fall short in overall efficiency and productivity, especially in late-stage manufacturing.

  10. Accelerating Gene Therapy Development For NEDAMSS 7/15/2025

    Discover how one family's race against time led to the creation of a groundbreaking gene therapy for their daughter, just 14 months after her ultra-rare disease diagnosis.