Insights On Drug Discovery

  1. Elucidating The Role Of IL-18 In NSCLC Integrated Analysis 1/23/2025

    Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.

  2. A Derivatization-Free LCMS Assay For 4β-hydroxycholesterol 1/23/2025

    Learn about a novel LCMS assay for 4β-hydroxycholesterol, a key biomarker for CYP3A activity. This derivatization-free method offers a faster and more efficient approach for clinical studies.

  3. Early Preclinical Development: A Successful Transition To cGMP Manufacturing 12/2/2024

    Explore the development steps that lead to an mRNA construct optimized for your requirements and that meets future-proof cGMP manufacturing requirements, thereby de-risking the development.

  4. Vector Technology For Improved Expression Control Of Biotherapeutic Proteins 11/19/2024

    Discover enhanced vector technology developed to enable better control of expression in cells, enhance titers, and improve expression stability for a range of biotherapeutic formats.

  5. Is Lipinski's Rule Of Five Still Relevant In Drug Development? 11/13/2024

    Some drugs violate multiple Ro5 elements but remain developable, while some molecules adhere strictly to the Ro5, but their properties are not conducive to development.

  6. cGMP-Ready Clonal HEK293 Cell Line For AAV, Lentiviral, And Adenoviral Vector Production 11/7/2024

    See how this advanced SKPT-HEK293 4G9 was able to provide a robust, CGMP-ready solution for efficient viral vector production, supporting a range of AAV serotypes and CAR-T Lenti-viral vectors for scalable manufacturing.

  7. Designing, Selecting, And Developing Bioconjugates For Clinical Success 10/24/2024

    Accelerate the development of complex bioconjugates to unlock new possibilities for targeted therapies and advance the next generation of precision medicine.

  8. Bioconjugates – An Increasing Diversity, A Blossoming Of Therapeutic Applications 10/24/2024

    Harness the power of bioconjugation to revolutionize targeted therapies, enhance drug efficacy, and reduce side effects, paving the way for more precise and effective treatments across a range of diseases.

  9. Breaking Barriers: Combining Cell Line Development Innovation With Improved Process Development Workflows To Streamline Path To FIH 10/16/2024

    Explore how KBI Biopharma’s SUREtechnology Platform™, powered by Selexis®, accelerates the development of complex biologics from early stages to first-in-human (FIH) trials, focusing on both speed and quality.

  10. Mastering The Art Of Developing A Successful Bispecific Antibody 10/3/2024

    Learn innovative strategies to overcome the complexities of bispecific antibody development, from intelligent design to efficient purification techniques.