Featured Articles

  1. A Scalable Single-Use Two-Step pDNA Purification Process 3/6/2024

    Evaluate the performance of a single-use two-step plasmid purification process, and see how it compares to the existing three-step purification method.

  2. High-Titer rAAV Production In Bioreactors Using Producer Cell Lines 3/6/2024

    Here, we detail the upstream process development and optimization for an AAV8-GFP proof-of-concept (PoC) producer single cell clone (SCC) in both batch and perfusion modes.

  3. Safer AAV Through Reduced Host-Cell DNA Encapsidation 3/6/2024

    While most hcDNA molecules outside AAV particles can be eliminated during downstream processing, encapsidated hcDNA molecules remain largely undetectable. Learn how to overcome this critical issue.

  4. Cost Modeling Comparison Of Bioreactors To Produce Adherent Cell Products 3/6/2024

    This study employs BioSolve software, a reference for cost analyses in the biopharmaceutical industry, to compare the upstream manufacturing costs between multitray stacks and the iCELLis™ bioreactor.

  5. Future Proof Your Process Scale Workflow 3/4/2024

    Discover how you can future-proof your process scale workflow, from starting bases to tangential flow filtration.

  6. Demand More From Your Oligo Synthesizer 3/4/2024

    The market for oligonucleotide therapeutics is expanding, and the pipeline is diverse. Gain insight into how you can fast-track your molecule's development with verified synthesizers, columns, and scientific support and expertise.

  7. Imagine The Future: Enhanced Oligonucleotide Synthesis 3/4/2024

    Learn about flexible control software that has revolutionized the way method creation, evaluation, and process optimizations for scale-up are completed.

  8. The Power Couple: CRISPR And Oligonucleotides 3/4/2024

    Drug design using CRISPR depends on long guide RNA (gRNA) sequences. Find out how this match between long oligos and CRISPR works.

  9. Five Essentials For Accurate Oligonucleotide Chemistry 3/4/2024

    Explore five key areas in oligonucleotide chemistry where improvements will have a huge influence on your synthesis quality.

  10. Insights Into GMP Manufacturing Of RNA-LNP Drug Products 2/29/2024

    Explore key considerations for manufacturing RNA-LNP drug products surrounding process and analytical development, automation, environmental monitoring, and strategic collaborations.