Discovery Research Articles

  1. Oncology Solutions: Accelerate Your Cancer Therapeutics Development 6/20/2022

    Aragen offers solutions from lead candidate selection to their development, preclinical trials, clinical trials, and GMP manufacturing under one roof.

  2. NanoAssemblr® Spark™: Freedom To Discover 4/14/2022

    The NanoAssemblr® Spark™ is ideal for nanomedicine formulation discovery and screening at microliter scales.

  3. Assessing A Platform for Accelerating Product Development 3/3/2022

    Examine an innovative approach to accelerating drug development, and learn the savings to drug developers from applying the approach across the industry portfolio of investigational drugs.

  4. LentiStable™ 3/1/2022

    We have generated suspension and adherent-based stable packaging and producer cell lines using an inducible system. Packaging cell lines stably integrate some of the components of the lentiviral system (Envelope, Gag/Pol and Rev, if required) into the cell genome.

  5. Plasmid DNA Capabilities 2/17/2022

    Our customized pDNA CDMO services offer research-grade, high-quality, and GMP materials.

  6. CHEF1™ Expression Technology 2/17/2022

    The platform accelerates development of cell lines for cGMP production by using robust procedures and reliable raw materials, including chemically defined media, adapted Chinese hamster ovary (CHO) cells, and proprietary expression plasmids, to rapidly produce high levels of recombinant protein.

  7. Adherent Versus Suspension Processes For Viral Vector Manufacturing 2/3/2022

    In adherent cell culture, cells are grown while attached to a substrate as monolayers. In suspension cell culture, cells are free-floating in the culture medium. Which offers more benefits?

  8. Formulation Development Strategy For Early Phase Human Studies 1/27/2022

    Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.

  9. Testing Cell Line Development Technology Platforms In Parallel 1/18/2022

    Access to multiple cell line development platforms — and the option to test them against one another — can minimize project risk, optimize titers, and differentiate vendor partners.

  10. Automated Bag Thawing System For CAR-T Cell Therapy Manufacturing 1/11/2022

    The performance of the VIA Thaw CB1000 is compared to thawing in a water bath. The VIA Thaw™ dry thawing system shows comparable performance to a water bath with less handling.