Discovery Research Articles

  1. Oncology Solutions: Accelerate Your Cancer Therapeutics Development 6/20/2022

    Aragen offers solutions from lead candidate selection to their development, preclinical trials, clinical trials, and GMP manufacturing under one roof.

  2. NanoAssemblr® Spark™: Freedom To Discover 4/14/2022

    The NanoAssemblr® Spark™ is ideal for nanomedicine formulation discovery and screening at microliter scales.

  3. Strategies For De-Risking Early-Phase Oral Small Molecule Drug Development 3/7/2022

    A team of experts discuss risk-reduction strategies, critical formulation considerations, and careful technology selection to stretch the often limited quantities of API available for early studies.

  4. Assessing A Platform for Accelerating Product Development 3/3/2022

    Examine an innovative approach to accelerating drug development, and learn the savings to drug developers from applying the approach across the industry portfolio of investigational drugs.

  5. Drug Substance Synthesis And Manufacturing 3/3/2022

    We take an agile and flexible approach with our customers programs, offering bespoke drug substance synthesis and manufacturing, helping to accelerate molecules from candidate selection to clinical proof-of-concept and onwards towards commercial scale.

  6. LentiStable™ 3/1/2022

    We have generated suspension and adherent-based stable packaging and producer cell lines using an inducible system. Packaging cell lines stably integrate some of the components of the lentiviral system (Envelope, Gag/Pol and Rev, if required) into the cell genome.

  7. Plasmid DNA Capabilities 2/17/2022

    Our customized pDNA CDMO services offer research-grade, high-quality, and GMP materials.

  8. CHEF1™ Expression Technology 2/17/2022

    The platform accelerates development of cell lines for cGMP production by using robust procedures and reliable raw materials, including chemically defined media, adapted Chinese hamster ovary (CHO) cells, and proprietary expression plasmids, to rapidly produce high levels of recombinant protein.

  9. Adherent Versus Suspension Processes For Viral Vector Manufacturing 2/3/2022

    In adherent cell culture, cells are grown while attached to a substrate as monolayers. In suspension cell culture, cells are free-floating in the culture medium. Which offers more benefits?

  10. Formulation Development Strategy For Early Phase Human Studies 1/27/2022

    Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.