Discovery Research Articles

  1. Testing Cell Line Development Technology Platforms In Parallel 1/18/2022

    Access to multiple cell line development platforms — and the option to test them against one another — can minimize project risk, optimize titers, and differentiate vendor partners.

  2. Automated Bag Thawing System For CAR-T Cell Therapy Manufacturing 1/11/2022

    The performance of the VIA Thaw CB1000 is compared to thawing in a water bath. The VIA Thaw™ dry thawing system shows comparable performance to a water bath with less handling.

  3. N-Linked Glycan Analysis For Complex Glycoproteins 12/20/2021

    An established cell line and a bench-scale manufacturing process for a complex glycoprotein produced high quality material but had a low yield and was not scalable.

  4. Crystallization Of Challenging Pharmaceutical Targets To Aid Drug Discovery 12/13/2021

    Discover a few successful strategies used when growing crystals of challenging pharmaceutical targets to aid drug discovery and two case studies performed by an experienced team of crystallographers.

  5. Raman vs. MIR Spectroscopy For Mammalian Cell Culture Monitoring 12/9/2021

    A direct comparison between the two technologies was conducted to investigate which system is more suitable for analyzing mammalian cell culture(s).

  6. Process Development For AAV Vector Production In Suspension Cells 11/19/2021

    Review experiments for the adaptation of the HEK293 suspension cell line for transient transfection and scalable adeno-associated virus (AAV) production.

  7. How Collaboration Helped A Global Biopharma Fast-Track Novel Molecule Development For Global Licensing 9/2/2021

    Discover how a Pharma-CRO partnership can extend beyond company borders into wholistic drug development activities for global licensing.

  8. Multi-Discipline Drug Discovery Capabilities & Deep Expertise Within The Drug Development Pathway 5/11/2021

    Learn about the Specialized Services that customers often seek that require a discrete expertise and technology toolbox not found in many CRO/CDMOs.

  9. Robust CHO Cell Expression Platform For High-Quality Biomanufacturing 3/16/2021

    Rapid development of high-quality cell lines is vital to biomanufacturing projects. How developers approach the fundamental steps can define their core biologics capabilities and keep projects on track.

  10. Navigating Regulatory And Development Milestones 9/17/2020

    This article addresses how early-stage biotherapeutic companies can avoid common pitfalls as they navigate the funding and regulatory processes to bring novel therapeutics from research to market.