Drug Development Applications & Studies
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Method Transfer Of A USP Organic Impurities Method To An Arc HPLC
10/7/2022
Learn about a global interlaboratory method transfer study of a USP impurities method that was conducted at eight participating sites.
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Higher Order Structure Of Proteins By Circular Dichroism Spectroscopy
9/30/2022
Learn more about the analytical development for mAbs and recombinant proteins
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Streamline Method Validation In Pharmaceutical Product Development
9/21/2022
Method validation is a time-consuming activity prone to human error. Find out how a method validation manager can provide a single, comprehensive solution for your validation activities.
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Method Development of Ten Antibiotic Compounds Using A Systematic Screening Protocol
9/21/2022
Effective method development of LC and LCMS methods typically involve highly experienced scientists with a wealth of knowledge that has been handed down throughout their organization. For some particularly challenging and complex mixtures this experience may not be enough. Learn how Waters leveraged a generic systematic protocol to separate a variety of APIs in a single run.
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Sequencing Of Synthetic Oligonucleotides And Their Impurities
9/20/2022
We demonstrate an automated, compliance-ready liquid chromatography-mass spectrometry (LC-MS) workflow for sequence confirmation of oligonucleotides and their impurities.
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In-Process Media Monitoring Using LC-MS And Automated High Throughput Microbioreactor Systems
8/23/2022
Explore a comprehensive LC-MS methodology, workflow, and batch analysis software that allows bioprocessing engineers to quickly and easily run and process large number of samples.
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Automating Rapid High-Throughput LC-MS mAb Subunit Screening
8/23/2022
We present a fully automated workflow for sample preparation and LC-MS analysis of mAbs obtained directly from complex samples such as spent cell culture media including host cell protein.
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Secondary Packaging Strategies For Commercial Launch Of A Biologic
8/17/2022
A commercial packaging solution can be the first and enduring impression that a sponsor company makes on a patient, and its suitability can impact a biologic’s commercial success.
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A Versatile Application For Rapid Mass Confirmation And Purity Assessment Of Biotherapeutics
7/18/2022
We explore a streamlined integrated workflow for data acquisition, processing and reporting of deconvoluted mass data for biotherapeutics, deployable in regulated and non-regulated environments.
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Transferring N-Glycan HILIC Separations Between UPLC And HPLC
7/18/2022
We demonstrate that comparable chromatographic profiles and relative quantitation can be achieved with the larger particle size column at HPLC-compatible pressures, albeit with an increase in sample load, mobile phase use, and most importantly, analysis time.