Catalent Biologics Content
-
Intensified Fed-Batch Process Using N-1 Perfusion And ambr 15
10/9/2019
Learn how to combine N-1 perfusion with the ambr®15 bioreactor system to create a powerful tool for rapid development of a highly efficient cell culture process.
-
Ensuring Success In Early Biopharmaceutical Formulation Development
6/10/2019
Biopharmaceuticals tend to be highly unstable. A pilot formulation study at the early drug substance development stage can make things considerably easier at the manufacturing stage.
-
Comparing Batch Versus Continuous Modes
6/10/2019
This case study compares the productivity of purifications running in batch versus continuous mode. Both Protein A capture resins demonstrated increased productivity with lower buffer volume in continuous mode.
-
A Novel Purification Tool's Effects On HCP Reduction, Turbidity
6/10/2019
This study involved a DoE approach to investigate effects of pH and conductivity on the turbidity, yield, and impurity clearance of the Emphaze™ AEX Hybrid Purifier and efficiency of the Protein A capture step.
-
High-Throughput Formulation Development For High-Concentration mAbs
6/10/2019
How a high-throughput, microwell plate platform can be used to economically screen a model IgG1 mAb at 120 mg/ml in 96 formulations while minimizing protein consumed and generating large amount of data.
-
Strategies For Process Characterization, Late Phase Development
6/10/2019
We propose a stepwise approach for the definition and execution of Process Characterization for the production of a monoclonal antibody to improve the efficiency and effectiveness of the process.
-
Achieving Unique Synergies In Antibody Expression
6/10/2019
This poster demonstrates how a cell line development technology combined with a platform for cell line selection shortens timelines and generates productive, stable, high expressing cell lines.
-
Transitioning From Vial To Prefilled Syringe
Understand how formulation development for a prefilled syringe affects manufacturing, driving the industry toward optimizing delivery of injectable products and, ultimately, improving patient care.
-
Overcoming Formulation Challenges For mRNA, High-Concentration Proteins
Increased demand for protein delivery and the emergence of advanced modalities – including mRNA – are introducing new challenges to the development lifecycle, such as high-concentration formulations.
-
Get Your Biologic To Clinic And Market Faster
We are your one integrated partner with the expertise to get your therapeutic product to market faster, helping you accelerate, simplify, and de-risk your biologics.