Newsletter | June 4, 2025

06.04.25 -- Tariffs On Toys … And API? Biopharma As The Next Battleground

SPONSOR

Take a tour of Nanoform's best-in-class nanodevelopment capabilities, setting new standards in innovation. Their highly specialized team excels in creating unique nanoparticles for both small and large molecule APIs. With 14 development lines for small molecules and 5 for large molecules, Nanoform offers unmatched scalability and precision. Leveraging cutting-edge technology, they produce nanoformed materials as small as 10 nanometers. Learn more

INDUSTRY INSIGHTS

Local Delivery For Treatment Of Lung Cancer

Explore two studies where lung cancer therapies were delivered to the lung by dry powder inhaler in a rat model and evaluated for efficacy, confirming local delivery is a promising route to treat lung cancer.

Nasal Vaccine Development, Manufacturing, And Device Selection

When developing a nasal delivery program, a partner with experience in development and manufacturing techniques who can see a program through small-scale clinical to commercial supply is crucial.

Transforming A Liquid Protein Solution Into A Solid Oral Dosage Form

Unlocking the potential of oral protein therapeutics requires innovative formulation and manufacturing strategies to overcome stability, absorption, and bioavailability challenges.

FEATURED EDITORIAL

Tariffs On Toys … And API? Biopharma As The Next Battleground

Outsourcing drug development and manufacturing is an attempt at purposeful action in a web of interdependent contingencies. The contingency top-of-mind today is President Trump’s tariff strategy, and global "negotiations" that have ushered in a supply-chain disquietude.

Patient Voices And AI: Analyzing Sentiment To Improve Generic Drug Oversight

Employing multiple AI models to analyze public sentiment of generic drugs minimizes bias and enhances reliability. This makes AI a proactive tool for pharmaceutical quality assurance.

INDUSTRY INSIGHTS CONTINUED

Expanding The OSD Toolbox Through Lipid Absorption Onto Powder Substrates

Consider innovative solutions for improving the solubility and bioavailability of poorly soluble compounds in solid oral dosage forms to enhance drug delivery and therapeutic effectiveness.

CMC And Clinical Strategies For Developing Injectable, Oral Peptide Drugs

In this session, Chief Scientific Officer Dr. Andy Lewis delves into the key drivers shaping peptide drug development and explores innovative delivery options to enhance therapeutic outcomes.

Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives

A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.

SPONSOR

Join Outsourced Pharma Live on June 11th at 2pm ET for a virtual panel discussion on the specific challenges of biologics development that must drive CDMOs to embrace more flexible approaches. Registration is free thanks to the support of Curia.

SOLUTIONS

From FIH Through Phase 3: GMP Manufacturing Capabilities

From first in human (FIH) through to phase 3 clinical supplies manufacturing at our MHRA-approved and Home Office-approved (I-IV) GMP facility, Trent Gateway.

Capacity Update April 2025: Analytical Services

Gain a strategic edge through customized solutions, reliable metrics, and a clear pathway to successful downstream testing, ensuring your therapeutics reach patients faster.

South Haven cGMP Manufacturing Services And APIs

Learn how our chemical manufacturing facilities are equipped to support a wide range of projects with on-site pilot plants and large-scale commercial capabilities for manufacturing high-quality APIs.

Capacity Update April 2025: Analytical Services

Caddy Hobbs, Ph.D., takes an in-depth look at our analytical services, which support the full drug development lifecycle — from early development through to commercial manufacturing.

OUTSOURCED PHARMA CAPACITY UPDATE

Find Your New CDMO At Outsourced Pharma Capacity Update

CDMOs in biologics, cell and gene, and small molecule share their capabilities and available capacities. See for yourself why this virtual event has become a wildly popular resource to identify options for your development and manufacturing needs.

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