Plasmid production requires a coordinated effort across a number of teams for both sponsor companies and manufacturing partners. Moving parts across upstream and downstream processes require close collaboration and transparent communication. It is crucial to ensure that chromatography steps are efficient to properly capture the work from the upstream team.
Establishing and maintaining a seamless flow of communication between upstream and downstream teams will help to correctly set up process parameters for successful scale down and scale up, and integrated project teams will enhance smooth transitions between teams. Learn how an integrated project teams approach and efficient project management help to maintain timelines and avoid detrimental delays.