Small Molecule Outsourcing STREAM

  1. Improving Bioavailability, Drug Loads, And Pill Burdens Of Solid Dispersions 9/10/2024

    Explore the pros and cons of marketed amorphous solid dispersions with so-far unpublished data as well as a green alternative to ASDs: best-in-class nanotechnology to manufacture nanocrystals.

  2. Improve The Bioavailability Of Poorly Soluble Drugs 3/19/2024

    KinetiSol is a fusion-based, solvent-free process that utilizes frictional and shear energies — in a fraction of the time of other amorphous solid dispersion technologies.

  3. Cambrex Scientist Spotlight: Luigi Bellone 1/29/2025

    Luigi Bellone, Head of Quality Assurance in Paullo, Milan, brings over 20 years of experience in quality assurance (QA), quality control (QC), and regulatory compliance within the pharmaceutical industry.

  4. Simultaneous Spray Drying: Dry Powder Inhaler Combination Formulations

    The simultaneous spray drying of multiple ingredients is a powerful technique for making inhaled products with multiple actives. Examine how novel techniques can make these products a reality.

  5. Formulation Of Crystalline Nanoparticles Enabling Superior Drug Load 8/13/2024

    Explore how bioavailability of poorly soluble APIs can be improved and patient compliance enhanced by reducing the size or number of tablets that a patient must take to achieve the required dose.

  6. Local Delivery For Treatment Of Lung Cancer

    Explore two case studies where lung cancer therapies were delivered to the lung by dry powder inhaler in a rat model and evaluated for efficacy, confirming local delivery is a promising route to treat lung cancer.

  7. Rapid, Material-Sparing Feasibility Screening For Hot Melt Extrusion

    Discover a screening process to quickly assess HME feasibility that yields more accurate predictions for API loading and degradation while saving material and time compared to traditional approaches.

  8. Rapid Developability Assessment Of Early Phase Molecules

    A case study illustrating how to use PBPK modeling, the developability classification system, and the biopharmaceutics drug distribution classification system to facilitate development of a molecule.

  9. Nanoparticle Enabled Formulation And Drug Delivery Solutions

    Discover how revolutionary and environmentally sustainable nanoparticle technologies coupled with innovative formulation approaches can address drug solubility issues and add value for patients.

  10. From Bench To Batch: Strategies For Scaling HPAPI Production

    Highly potent materials bring additional challenges to manufacturing processes. Examine considerations for optimizing HPAPI production methods to reduce risk and deliver therapies to patients with speed.