Outsourced Pharma App Notes & Case Studies

81. Innovating In The Viscosity Design Space For Handheld Combination Products: A New 2.25 mL Autoinjector Platform 5/12/2021

    Discover an autoinjector platform that reconciles the demands of biologics with safety, reliability, and ease of use during self-injection.

82. Probing The Source Of An Unstable Impurity And Controlling Its Formation At Release 4/19/2021

    A critical step in an extended-release drug product analysis is the extraction during impurity and assay sample preparation. When both the drug substance and the impurity are unstable, this is especially challenging.

83. Radiance Label-Free Monitoring Of AAV Transfection In HEK293 Cells 7/13/2020

    LumaCyte’s Radiance® instrument has the potential to improve the characterization of cell-based AAV transfection and production, improving the efficiency and accuracy of both processes and shortening development time.

84. How Collaboration Helped A Global Biopharma Fast-Track Novel Molecule Development For Global Licensing 9/2/2021

    Discover how a Pharma-CRO partnership can extend beyond company borders into wholistic drug development activities for global licensing.

85. Balancing Safety And Simplicity In A New Generation Of Emergency Auto-Injector 1/20/2021

    In an emergency, people tend to panic and find it difficult to make rational decisions, with the result that even the simplest task can become complex. So, an EAI has to be capable of delivering a life-saving dose of drugs quickly and effectively, no matter who is using it. Read how one manufacturer balances the fine line between adding enough fail-safe features but avoiding making the device too complicated for inexperienced users.

86. Executing A Closed Connected Process From Start To Finish 12/22/2020

    Recommendations from our execution of a closed and connected mAb process from design considerations to scale-up, including the small-scale modeling that directed our manufacturing scale processes.

87. The Effect Of Rocking Rate And Angle On T Cell Cultures Grown In Expansion Systems 2/23/2020

    Ensuring optimal and maximal T cell production is critical for adoptive immunotherapy and its continued success. The Xuri Cell Expansion System is an important component of the clinical manufacturing process so we sought to investigate the effect of the rocking rate and angle on the expansion of T cells.

88. Developing A Continuous Large-Scale Perfusion Cell Culture Process 9/25/2020

    The key benefits of perfusion processes are compact process design, flexibility, increased productivity, increased yield, and consistent product quality. 

89. Looking Back And Moving Forward In The Fight Against SARS-CoV-2 1/26/2021

    In a recent roundtable discussion, a panel of experts offered their insight on what challenges they have seen during this crisis and what they believe we can learn from them going forward.

90. Four Reasons For The Rise In Blister Packaging 5/13/2021

    Blister packaging, not long ago considered a less significant segment of the North American pharmaceutical packaging industry, is now outpacing most other industry segments. The pharmaceutical manufacturing industry has witnessed a significant increase in the number of drug approvals by the FDA over the past few years leading to several packaging innovations. Here are the factors that are driving blister to the forefront of pharmaceutical packaging, and at an even faster rate than its current growth.