Outsourced Pharma App Notes & Case Studies

  1. Improve Bioprocessing Efficiency With A Standardized Automation Platform 3/9/2021

    Designed specifically for the biomanufacturing industry, Cytiva's Figurate automation is a portfolio of automation platform solutions powered by the reliability of Emerson’s DeltaV.

  2. Developing A Continuous Large-Scale Perfusion Cell Culture Process 9/25/2020

    The key benefits of perfusion processes are compact process design, flexibility, increased productivity, increased yield, and consistent product quality. 

  3. How To Prepare For Future Viral Vector Manufacturing Technologies And Platforms 3/1/2021

    The challenges and shortage of vector production reflect the fact that these materials and products are having such strong clinical success. Let’s celebrate the reason for this demand. To meet it, we need to industrialize and rethink how we transition from what has historically been carried out in translational clinical centers at smaller scale, using flasks and open systems, towards commercial production and methodologies.

  4. Wound Healing Assays: High-Throughput, Accurate And Reproducible 4/12/2021

    Wound healing assays are widely used to study cell migration. Traditional procedures include manually measuring the wound width with a stereomicroscope which is inconsistent, time consuming, and fraught with human error. Apply powerful technology for accurate and reproducible data in a high-throughput way.

  5. Case Study: Reduced Risk, Spending, And Work In A Global Diabetes Trial 10/29/2020

    And as one leading multi-national pharmaceutical company recently learned, managing ancillary materials can be a challenge every bit as complex as the trial itself.

  6. Purifying Tagged Proteins Using ÄKTA Go Protein Purification System 2/3/2020

    ÄKTA go is a small and compact liquid chromatography system that allows researchers to perform routine protein purification with ease while allowing for efficient use of bench and cold cabinet space.

  7. Clinical Supply Global Optimization: Managing Complex Global Drug Distribution And Expiry 1/12/2021

    A global top-ten pharmaceutical company was sponsoring a complex, 8-year Phase III trial across 43 countries. The Sponsor was under intense pressure to reduce trial costs and leverage internal resources. Ultimately, study sites began to run out of medication. They realized that the trial could be better managed if it was outsourced. 

  8. Standardizing Process Characterization And Late Phase Development 11/18/2019

    For therapies with early success now progressing toward commercial manufacturing, understanding the operational, regulatory, and quality connections is critical for successful filing and launch. This case study proposes an approach for process characterization to produce a monoclonal antibody, specifically at the drug substance biomanufacturing step, to improve efficiency and effectiveness.

  9. Automated High Throughput mAb Purification Using Fibro Technology 4/21/2020

    Read how the Fibro PrismA unit provides a time advantage with comparable recovery and product quality attributes to resin-based column.

  10. Viral Vectors, Vaccines - A New Era Of Collaborative Design 1/15/2021

    Companies often turn to CDMOs to bring vector-based products to market. So, it is important that they know how to assess a CDMO’s capabilities for helping them achieve their goals.