Milliporesigma Brochures

  1. Cellvento® 4CHO-X Brochure

    The new Cellvento® 4CHO-X Expansion Medium supports cell expansion including N-1 perfusion for Chinese Hamster Ovary (CHO) cell lines.

  2. Medium For Producing High AAV Titers In Multiple HEK293 Cell Lines

    Discover a chemically defined medium optimized for AAV production that has been streamlined and cell culture media components incorporated to increase media stability and reduce protein oxidation.

  3. Analytical Development And Characterization For mRNA

    Meet your mRNA product's specific needs with assay packages that provide the product and process knowledge needed to develop a quality target product profile and identify critical quality attributes.

  4. Viral Clearance Services

    Ensure safety with expert-led viral clearance studies. Our global team delivers regulatory-compliant, scientifically robust solutions to eliminate viral risks and support your product’s success.

  5. A Transfection-Based Solution With Proven Performance At Scale

    The VirusExpress® 293 AAV Production Platform offers a transfection-based solution using a suspension-adapted cell line, which is GMP banked and characterized chemically defined medium, and a process with proven performance at a clinically relevant scale.

  6. EX-CELL® Advanced CHO Fed-Batch Medium

    EX-CELL® Advanced CHO Fed-Batch Medium is chemically defined, animal component free, and contains no hydrolysates or components of unknown composition. The formulations were developed using mulitvariate analysis of 10,000+ data points that included performance, physical, regulatory, and safety design specifications.

  7. Optimization Of Benzonase® Endonuclease Use In Virus Purification

    The use of Benzonase® endonuclease additionally increases the yield in virus purification, protects the downstream chromatography and filter devices from fouling and reduces feed stream viscosity. In this document we will provide you guidance on how to plan and set up a Design of Experiments (DoE) optimization experiment of Benzonase® endonuclease in your viral gene therapy process.