Product/Service

Xcelodose® S Precision Powder Micro-Dosing System

Source: Capsugel® | Lonza Pharma & Biotech

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With the Xcelodose® system, creating manufacturing batches for clinical trials and small-scale production has never been easier or more precise. That's because this unique technology allows companies to fill capsules with drug substances alone, thereby eliminating the need for excipient compatibility and preformulation activities.

Click Here To Download:
Product Brochure: Xcelodose® S Precision Powder Micro-Dosing System
Datasheet: Xcelodose® System RH Control Unit
Datasheet: Xcelodose® Accessories
Datasheet: Xcelohood™ Containment Hood
Video: Xcelodose® S Precision Powder Micro-Dosing System

With the Xcelodose® system, creating manufacturing batches for clinical trials and small-scale production has never been easier or more precise. That’s because this unique technology allows companies to fill capsules with drug substances alone, thereby eliminating the need for excipient compatibility and preformulation activities. Not only can the Xcelodose system precisely dispense amounts as low as 100 micrograms and up to 100 milligrams and beyond, but its sophisticated software also records the weight of the drug in every capsule. Plus, it can accurately fill 600 capsules per hour for extended periods of time.

By implementing the Xcelodose system, pharmaceutical companies benefit from a shorter drug development process by reducing the need for costly and time-consuming stability studies, not to mention the avoidance of labor costs and possible inaccuracies associated with hand filling. This in turn reduces the time taken to reach the 'first in man' clinical trial decision point, which allows an increase in throughput of candidate compounds for development.

Xcelodose® Benefits

  • Even 'Faster Time to First in Man' with precision, speed, and accuracy
  • Fills with precision at speeds of over 600 capsules/hour at ~2% RSD – approximately 10x faster than filling by hand, and 50% greater throughput than the previous version of Xcelodose®
  • Greater robustness over longer production runs
  • Additional software functionality
  • Integral High Throughput Unit available
  • No internal pneumatics – machine is much quieter
  • Allows filling of API direct into capsules, with no need for excipients, and can thereby save up to 6 months’ development time by reducing the need for formulation development and stability testing
  • Accurate drug records for the monitoring of batches and individual capsules – the weight of each capsule and event is recorded
  • Doses as low as 100 micrograms for precise drug trials
  • Capsule size change can be achieved in minutes – change parts sizes 00 to 4 available
  • Can be tailored to fill any powder, including blends
  • Particularly suitable for manufacture of Phase I clinical supplies
  • Wide range of optional extras and accessories available

Click Here To Download:
Product Brochure: Xcelodose® S Precision Powder Micro-Dosing System
Datasheet: Xcelodose® System RH Control Unit
Datasheet: Xcelodose® Accessories
Datasheet: Xcelohood™ Containment Hood
Video: Xcelodose® S Precision Powder Micro-Dosing System