Process & Scale-up Chemistry
Our integrated project teams are supported by a highly experienced and dedicated group of scale-up chemists.
Our integrated project teams are supported by a highly experienced and dedicated group of scale-up chemists (ex-Merck, Aventis, Roche, GSK and Ultrafine). Working with purpose-built reactor rigs (reaction temperature range <-70˚C up to 180˚C), large-scale synthesis and purification equipment, added value is delivered to customers by efficient in-house synthesis of key project intermediates (up to kilogram quantities) and active pharmaceutical ingredients (up to ~500g quantities) for preclinical toxicological studies.
As integrated drug discovery projects progress towards late-stage lead optimization, members of the scale-up team are deployed within the project teams to engage in early process chemistry research and development support. This enables seamless process transfer to our client's pilot plant, or to a CRO of their choice, thus avoiding delays that can often be experienced post candidate nomination.
Products/Services
- Medicinal Chemistry
- Computer-Aided Drug Design
- Synthetic Chemistry
- Analytical Chemistry
- Process & Scale-up Chemistry