Product/Service

Licaps® Capsules

Source: Capsugel, a Lonza Company

Licaps® Capsules

Licaps® capsules are two-piece gelatin capsules that have been specially designed to be sealed for secure containment of liquids and semi-solids. The Licaps capsule, in combination with a liquid fill, provides an attractive and viable dosage form, particularly for poorly soluble compounds.

Click Here To Download:
Product Brochure: Liquid Formulations In Licaps® Capsules
White Paper: Using Hard Gelatin Capsules To Meet New Market Demands

Licaps® capsules are two-piece gelatin capsules that have been specially designed to be sealed for secure containment of liquids and semi-solids. The Licaps capsule, in combination with a liquid fill, provides an attractive and viable dosage form, particularly for poorly soluble compounds.

Are you looking for a new way to overcome difficult formulation challenges that utilize non-aqueous materials?

Licaps are compatible with a wide range of excipients which may improve the solubility and bioavailability of your drug. Licaps capsules have low oxygen permeability, and have dissolution characteristics that may be useful for sustained release applications. A liquid fill not only enables the easier manufacture of small batches when minimal quantities of active are available, it also offers improved content uniformity of low dose compounds. The use of hot melts is also viable with Licaps, as they may be filled at temperatures up to 70° C. And dust-free production enhances the ability to work with potent compounds.

Do you need to move quickly to get your product to market?

Capsugel can be the extra set of hands required to support your needs during development, technology transfer and market introduction. We can test your formulation to assure compatibility with Licaps, as well as run filling trials on the LEMS™ machine in our research center. We also have a parternship in place with Eurand and work closely with Aptuit in Europe, and Aptuit US, who offer contract development and manufacturing services for Licaps and LEMS™.

Licaps capsules are sealed using an innovative technology on a machine known as LEMS™ - Liquid Encapsulation Microspray Sealing. This process eliminates the need for banding the capsules, and the easy operating characteristics of the LEMS™ machine enable one technician to simultaneously supervise both the filling and sealing operations.

As with all Capsugel products, you can be assured of the highest quality product and service. Licaps capsules are manufactured in a GMP facility that meets ISO 9000 certification criteria. Computerized process control stations monitor key manufacturing process parameters, and a certificate of analysis is included in every production batch.

Click Here To Download:
Product Brochure: Liquid Formulations In Licaps® Capsules
White Paper: Using Hard Gelatin Capsules To Meet New Market Demands