Newsletter | March 5, 2025

03.05.25 -- How Do We Categorize CDMOs?

SPONSOR

Enhancing the bioavailability of poorly soluble APIs with Spray Drying.

This white paper from Upperton Pharma Solutions explores the use of spray drying in pharmaceuticals, its role in enhancing the bioavailability of poorly soluble APIs, and its application in creating dry powder pulmonary and nasal dosage forms. Click to learn more.

FEATURED EDITORIAL

How Do We Categorize CDMOs?

Are we on the same page? Do we need to be? That is, how do we differ on what might seem like the mundane defining of CDMOs as small, medium, or large? Some readers have been asking. How might this determination be relative and important to individual sponsors? Our Advisory Board members weigh in.

WFI Production Methods: Multi-Effect Distillation Vs. Vapor Compression

The two most common hot water for injection (WFI) generation methods are multi-effect distillation (MED) and vapor compression (VC). Here, the author reviews significant differences between each method in terms of operational principles and energy efficiency.

INDUSTRY INSIGHTS

The 3 Cs You Should Expect From Your Pharma Service Provider

Consider these important factors when weighing your contract service provider options. These “Three Cs” can indicate whether a service provider has the capabilities desired by a drug sponsor.

Developing And Manufacturing Minitablets To Extend Drug Lifecycle

Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.

Overload Setting – Tricks And Techniques

Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.

Less Mess, Less Stress, Best Expressed: An Alternative To Spray Drying

Although well-established processes, spray drying and hot-melt extrusion can be outperformed in bioavailability, cost-savings, manufacturing speed, environmental impact, and more.

Seizing Market Share Pre-Patent Expiry: The Evolution Of A CDMO Partnership\

The dynamic pharmaceutical landscape demands agility and strategic foresight. Explore how leveraging a key partnership helped to overcome a looming patent expiry for a second-generation acne medication.

Solutions For Accelerated Pharmaceutical Development

Review an integrated service package designed to simplify and accelerate the development pathway, even for APIs with challenging properties such as low aqueous solubility and poor bioavailability.

SPONSOR

Webinar: 'Nanoforming - the single pill technology' - how high drug load nanocrystalline tablets lower pill burden delivering better products for patients

Enzalutamide and apalutamide, used for advanced prostate cancer, are not druggable in their crystalline form due to low solubility, so they are marketed as amorphous solid dispersions. Join on March 12th to learn how Nanoforming these drugs into high-load nanocrystals can reduce pill size, enhance performance, and extend market exclusivity while benefiting patients.

SOLUTIONS

A Pillar Of Innovation, Sustainability, And Pharmaceutical Excellence

Discover how SK pharmteco's innovative La Porte, Texas facility combines advanced technology, sustainability, and strategic efficiency to redefine excellence in pharmaceutical manufacturing.

Award-Winning Technology For Successful GMP Manufacturing

Nanoform’s GMP facility utilizes its award-winning Controlled Expansion of Supercritical Solutions (CESS) technology for the manufacture of API nanoparticles to GMP standards.

Cambrex Scientist Spotlight: Jonas Nilsson

Jonas Nilsson, Principal Scientist based in Karlskoga, Sweden, leads a team of synthetic chemists focused on process development and optimization.

AI-Enabled Route Scouting Service

Lonza's Route Scouting Service empowers biotech partners to overcome the complexities of API development and bring life-changing medicines to market faster.

OUTSOURCED PHARMA CAPACITY UPDATE

Find Your New CDMO At Outsourced Pharma Capacity Update

CDMOs in biologics, cell and gene, and small molecule share their capabilities and available capacities. See for yourself why this virtual event has become a wildly popular resource to identify options for your development and manufacturing needs.

Connect With Outsourced Pharma: