Newsletter | March 27, 2025

03.27.25 -- Explore mRNA Advancements With Engineered T7 RNA Polymerase

Enhancing Safety And Efficacy Of mRNA-Based Therapeutics

This white paper examines the challenges of dsRNA in mRNA therapeutic safety and presents data on how Codex® HiCap RNA Polymerase boosts mRNA yields while reducing dsRNA byproducts.

 

Getting IVT Right: Improving Capping Efficiency

As regulatory standards for mRNA vaccines and therapeutics tighten, we're exploring how Codex® HiCap RNA Polymerase improves capping efficiency, cuts costs, and streamlines IVT manufacturing.

 

Streamline The Path From Discovery To Patient: Simpler RNA Manufacturing

Review the benefits of a co-transcriptional capping RNA polymerase engineered to produce synthetic RNA to meet these increasing demands for safety and cost-effectiveness.

 

Transcribing RNA With Higher Purity, Activity While Using Less Cap Analog

Uncover how we were able to enhance RNA manufacturing with HiCap T7 RNA Polymerase, minimizing dsRNA, boosting expression, and reducing capping costs for superior therapeutic development.

 

SOLUTIONS

Breaking Barriers With Mutant T7 Polymerase

Discover how advanced mRNA manufacturing innovations, including optimized RNA synthesis and scalable LNP encapsulation, are accelerating therapeutic development.

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Codex® HiCap RNA Polymerase

Codex® HiCap RNA Polymerase overcomes IVT limitations, enhancing safety, cost-effectiveness, and performance to advance mRNA therapeutics and personalized medicine.

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