Newsletter | February 18, 2025

02.18.25 -- Essential Resources And Expert Insights For Preclinical Drug Development

Best Practices To Reduce Animal Use In Toxicology Studies

Experts share methods for minimizing the number of animals used in toxicology studies while ensuring robust and reproducible findings, including the advantages and limitations of each method.

 

How Do I Select The Right Species For My Toxicology Program?

Dive into the scientific rationale driving species selection for your nonclinical program, including how in vitro species comparison studies can help to determine the right species for your in vivo program.

 

Key Considerations In Nonclinical Cell And Gene Therapy Studies

This scientific journal reviews guidelines and crucial factors for nonclinical cell and gene therapy development, focusing on strategies to address challenges, improve study efficiency, and enhance translational opportunities from safety assessment to first-in-human trials.

 

A Changing Paradigm For Non-Rodent Species In Nonclinical Safety Studies

With the increase of historical data and wider regulatory acceptance, the miniature swine model can support a variety of research areas due to their availability, physiological similarities to humans, and lower cost compared to other non-rodent models.

 

Nonclinical Safety Testing Guide

Are you equipped with the tools you need to plan your IND-enabling studies? Review this essential checklist to help plan your preclinical safety assessments and ensure successful regulatory submissions.

 

SOLUTIONS

Preclinical Research Services

Industry leader in preclinical safety assessments across various therapeutic areas. 30+ years of experience in full range of in vivo non-GLP and GLP studies in both rodent and non-rodent species.

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