CELL AND GENE OUTSOURCING
PEI And Non-PEI Transfection Solutions For High Titers And Production
Discover optimized AAV production with polyethylenimine (PEI) and non-polyethylenimine transfection solutions that are designed to boost titers and streamline scalability.
Tailored CMC Solutions That Meet Needs Of Novel Molecular Biologic Formats
Explore an integrated drug substance/drug product CMC strategy and technical case studies that provide insight into delivering product-specific solutions and enabling the acceleration of novel molecular formats.
The Blazar® Platform In A Minute
The Blazar® Rodent Panel from the BioReliance® portfolio can speed cell line characterization and bulk harvest lot release testing. This degenerate PCR-based method accelerates characterization by reducing timelines by up to 80% and replaces the use of animals.
Meet The Experts: Part 4 – Applications And Use Of Raman In Bioprocessing
Watch the fourth and final interview of this 4-part series to learn about Raman applications in bioprocessing from expert Célia Sanchez.
The Journey To Safety Through Viral Clearance
Discover a simple yet powerful solution for getting viral clearance studies done safely, thoroughly, efficiently, and on your timelines. Learn how to free your teams and trust your project.
Expertise In Commercial Fill-Finish For More Than 30 Years
Examine how a new high-speed aseptic filling line can help bring your product to market with speed and efficiency while ensuring safety and high product quality.
CRISPR Genome Editing Solutions From Discovery To Clinic
Examine how a partnership leveraging expertise in production for high-quality CRISPR gRNAs as well as cGMP manufacturing is supporting the clinical translation of CRISPR genome editing technologies.
Accelerate Your AAV Journey To IND And Beyond
Explore essential QC strategies in AAV gene therapy and learn how to address rcAAV detection, viral clearance per ICH Q5A, and impurity profiling using NGS to meet evolving regulatory demands.
Early Developability And Analytical Toolbox For The Production Of Multi-Chain Biotherapeutics
In recent years, the number of biotherapeutic molecules requiring more complex assemblies has greatly increased. Typically, these multi-chain molecules are no longer compatible with platform approaches and require a more agile approach to early developability and method d...
Optimization-By-Design — A Critical Factor In Viral Vector Scale Up
Learn how leveraging the expertise and capabilities of an experienced partner is a key factor in optimizing AAV processes using Design of Experiment (DoE), thereby reducing variability and risk.
MilliporeSigma Large Scale Capabilities Tour
A detailed look at MilliporeSigma’s new BioReliance® viral vector manufacturing facility and how we have employed the latest innovations and quality systems to deliver best-in-class gene therapy services.
Managing Risks In Injectable Drug Delivery
Gain insights pertinent to efficient and effective drug development. Understand and execute a risked-based critical thinking approach related to injectable drug packaging and delivery.
Sustainable Approaches To Oligonucleotide Manufacturing
An industry expert shares about sustainable Oligo manufacturing approaches that can save time, cost, and resources – while improving purity, quality, and scalability of these promising therapeutics.
Advancing Cell & Gene Therapies To Patients
Discover how we apply our expertise and know-how to efficiently advance your viral vector-based therapeutic through any phase, while enhancing quality and de-risking production.
Cell & Gene Therapy Development: Characterization Of Cellular Starting Material
Watch to gain valuable insights into the characterization of cellular source material for the development and manufacture of cell and gene therapy-based products.
Building A Strong Safety Culture In The Biopharmaceutical Industry
Explore how fostering a strong safety culture — rooted in accountability, collaboration, and proactive risk management — can drive operational excellence and long-term success in biopharmaceuticals.
A Faster, More Sensitive Approach To Virus Detection
Discover a faster, more sensitive approach to rodent virus detection that offers a targeted NGS workflow to help uncover contaminants traditional assays may miss.
Combining An MVA Technology Platform With Innovative Analytical Methods
Learn how this process development platform for MVA impacts vaccine manufacturing and supports the drug life cycle from process and analytical development through trials and commercialization.
Pioneering Solutions That Turn Hope Into Reality
The number of AAV-mediated therapies in clinical trials continues to rise, increasing demand for doses. A scalable platform is crucial to ensure a seamless transfer from pre-clinical to commercial.
Virus Filtration In Continuous Processing: Novel Approaches For Optimal Performance
Watch to explore two novel approaches that have been developed to overcome the limitation of a filter's viral retention performance in continuous processes.
Combining Expertise With Best-In-Class Technology
Members of the MilliporeSigma leadership team reflect on the longstanding experience of our BioReliance® viral vector manufacturing facilities. Our legacy experience, alongside our brand new facility and latest industry innovations, ensure we are a preferred partner t...
Purity As A Priority: Optimizing Safety Measures For rAAV Therapies
Watch to learn how rAAV vectors in gene therapy are addressing manufacturing impurities, risks to patient safety, and analytical methods for detection while aiding sponsors in regulatory compliance.
Mastering The Art Of Developing A Successful Bispecific Antibody
Learn innovative strategies to overcome the complexities of bispecific antibody development, from intelligent design to efficient purification techniques.
Viral Vector Manufacturing: Improve Efficiency With A Platform Approach
Learn more about the platform-based scalable suspension process for LVV production and how it is impacting CGTs advancing toward commercialization.
Meet The Experts: Part 3 - Chemometrics And Model Building
Watch part 3 of this 4-part interview series to learn about chemometrics and model building from expert Johan Cailletaud.
Biotherapy Characterization: Cell-Based Assays
MilliporeSigma Senior Scientist Agata Burzawa, MSc, explains how we can provide you with rich data sets to help you understand your complex biotherapy faster. Using limited volumes of samples for testing, our scientists employ leading technologies that integrate cytokine ...
Accelerate Development And De-Risk Gene Therapy Manufacturing
Join viral vector process and analytical development experts as they showcase strategies for developing robust processes and analytics for efficient and de-risked manufacturing.
A Rapid, Innovative Approach To Release Testing
Innovative molecular methods will allow mAbs manufacturers to deliver critical therapeutic agents to patients faster. Learn about a powerful tool that accelerates bulk harvest testing.
Critical Supply Chain And Logistics Considerations For Cell And Gene Therapy Management
Explore the unique challenges and complexities involved in key CGT logistics areas like donor and patient accessibility, critical raw materials management, and innovative temperature control equipment.
BioPhorum Raw Materials Risk Assessments
Torsten Schaderdorf provides an in-depth exploration of current regulations related to Raw Materials Risk Assessment, highlighting the risk criteria and raw material scope outlined in the BioPhorum guidelines.
