CELL AND GENE OUTSOURCING
Virus Filtration In Continuous Processing: Novel Approaches For Optimal Performance
Watch to explore two novel approaches that have been developed to overcome the limitation of a filter's viral retention performance in continuous processes.
Effective Supply Chain And QC Testing Through Collaborative Partnerships
Explore how cross-functional teams streamline cell therapy manufacturing and release for Phase 1 trials to meet patient timelines and ensure safe delivery of personalized treatments.
Advancing Viral Vector Manufacturing: The Importance Of The Cell Line
Explore the pivotal role of cell lines in viral vector manufacturing, a complex, multi-step process that has traditionally been both time-consuming and labor-intensive.
Optimizing Monoclonal Antibody Manufacturing For Commercial Success
Strategically optimize your upstream and downstream processes and decrease the timeline from optimization to commercial manufacturing.
Selecting Containers For Sensitive And Costly Cell & Gene Therapies
Explore the challenges related to packaging of cell and gene therapy products and proven solutions to enable speed to market and compatibility, performance of packaging materials.
How MilliporeSigma Promotes Quality And Risk Reduction
Learn how MilliporeSigma’s new facility was built with quality and risk reduction at the top of mind and its experts have the experience to support large-scale programs through commercialization.
Industry-Leading Lentiviral Titers Through Optimized Production Technology
See how VirusExpress' technology was optimized to provide industry-leading lentiviral titer and a streamlined approach to accelerate development timelines and de-risk manufacturing.
Meet The Experts: Part 4 – Applications And Use Of Raman In Bioprocessing
Watch the fourth and final interview of this 4-part series to learn about Raman applications in bioprocessing from expert Célia Sanchez.
Make More Lentivirus And Make It Right The First Time
Discover how you can achieve higher titers and robust yield with an optimized, end-to-end lentivirus platform, designed to maximize production and quality for the success of your cell or gene therapy.
Early Preclinical Development: A Successful Transition To cGMP Manufacturing
Explore the development steps that lead to an mRNA construct optimized for your requirements and that meets future-proof cGMP manufacturing requirements, thereby de-risking the development.
Optimization-By-Design — A Critical Factor In Viral Vector Scale Up
Learn how leveraging the expertise and capabilities of an experienced partner is a key factor in optimizing AAV processes using Design of Experiment (DoE), thereby reducing variability and risk.
BioPhorum Raw Materials Risk Assessments
Torsten Schaderdorf provides an in-depth exploration of current regulations related to Raw Materials Risk Assessment, highlighting the risk criteria and raw material scope outlined in the BioPhorum guidelines.
Quality Agreements: Defining Governance In CDMO Partnerships
Quality agreements serve a critical role within a CDMO-Sponsor partnership. Review the importance of aligning objectives, quality standards, and compliance frameworks to establish a robust foundation.
Sustainable Approaches To Oligonucleotide Manufacturing
An industry expert shares about sustainable Oligo manufacturing approaches that can save time, cost, and resources – while improving purity, quality, and scalability of these promising therapeutics.
Mitigating Risk Through Product Characterization
In this webinar, multiple approaches to characterizing the physico-chemical and structural attributes of therapeutic mAbs is presented with a focus on how it influences the resulting biological activity.
Practical Applications For Controlled And Safe Nucleic Acid Delivery
Explore the science behind LNP formulation development, from ionizable lipids to scalable manufacturing through case studies, screening strategies, and flexible approaches for advancing next-generation therapeutics.
Meet The Experts: Part 1 - Process Analytical Technology (PAT)
Watch part 1 of this 4-part interview series to learn about process analytical technology (PAT) from expert Stacy Shollenberger.
GMP-Focused Platform Processes For Microbial, pDNA, And mRNA
Mario Kraft, Director of Process Development at AGC Biologics' Heidelberg facility, explains how platform processes optimize microbial, plasmid DNA, and mRNA production.
Biotherapy Characterization: Cell-Based Assays
MilliporeSigma Senior Scientist Agata Burzawa, MSc, explains how we can provide you with rich data sets to help you understand your complex biotherapy faster. Using limited volumes of samples for testing, our scientists employ leading technologies that integrate cytokine ...
Meet The Experts: PAT, Raman Spectroscopy, And Chemometrics
Gain a better understanding of process analytical technology (PAT), Raman spectroscopy, chemometrics, and Raman applications in bioprocessing.
Expertise In Commercial Fill-Finish For More Than 30 Years
Examine how a new high-speed aseptic filling line can help bring your product to market with speed and efficiency while ensuring safety and high product quality.
Empowering Your Plasmid DNA Workflow
Unlock the full potential of your pDNA purification with advanced chromatography solutions and resins that tackle high viscosity and impurities to ensure superior quality and yield.
Viral Safety Of Biologics: What's Changing With The ICH Q5A Revision?
ICH Q5A is currently being revised to address recent scientific advancements. We'll discuss the expected changes and potential impact on viral safety strategies.
Improved And Rebalanced Plasmids To Ramp Up Your AAV Productivity
Growth in rAAV-based therapies is creating a need for dramatically increased production. Learn how AAV productivity can be optimized using platform technologies capable of affording significantly higher titers.
How To Bring Your LNP Formulation To Clinical/Commercial Manufacturing
Gain valuable insights into key considerations when selecting lipid excipients for LNP formulations and the process development steps necessary to advance them to GMP manufacturing and clinical trials.
Eliminate Risk From Your Viral Vector Tech Transfers
Explore strategies to simplify viral vector tech transfers, reduce risk, and maintain quality under tight timelines, as well as a case study that demonstrates how to streamline this critical process.
Biopharmaceuticals Development And Manufacturing: Wide-Ranging Expertise And Vertically Integrated Service
The company’s wide-ranging expertise and vertically integrated service offering translate to the ability to rapidly execute multiple projects from its state-of-the-art cGMP facilities while ensuring full process and product compliance at all stages of research, deve...
Pioneering Solutions That Turn Hope Into Reality
The number of AAV-mediated therapies in clinical trials continues to rise, increasing demand for doses. A scalable platform is crucial to ensure a seamless transfer from pre-clinical to commercial.
Combining Expertise With Best-In-Class Technology
Members of the MilliporeSigma leadership team reflect on the longstanding experience of our BioReliance® viral vector manufacturing facilities. Our legacy experience, alongside our brand new facility and latest industry innovations, ensure we are a preferred partner t...
Meet The Experts: Part 2 - Raman Spectroscopy
Watch part 2 of this 4-part interview series to explore Raman spectroscopy, one of the main PAT tools for monitoring bioprocess CQAs and CPPs, with expert Fabien Caron.