Mastering The Art Of Developing A Successful Bispecific Antibody

Shifting from single-function antibodies to complex bispecific designs presents unique challenges that require innovative approaches. Unlike conventional antibodies, bispecifics demand customized screening strategies to pinpoint the most effective format.

This in-depth webinar explores the key principles and best practices for designing successful bispecific antibodies. In it, Dr. Timothy Wood, Ph.D., Senior Scientist at Abzena focuses on intelligent bispecific design, with a particular emphasis on factors such as avidity, spacing, and the configuration of fragment antigen binding (Fab) and single-chain fragment variable (scFv) arms. Our systematic approach aims to streamline the screening process, enabling broad exploration while keeping designs efficient and minimal.

Attendees will learn:

• Key Design Considerations for Bispecific Candidates: Learn which elements to incorporate or avoid to optimize your bispecific antibody designs.
• Single-Step Purification for Enhanced Purity: Discover effective methods for improving antibody purity through efficient single-step purification processes.
• In-Depth Case Study on Screening Strategies: Gain valuable insights into the importance of screening multiple designs, supported by a detailed case study.

This webinar offers practical guidance for anyone involved in the development of bispecific antibodies, providing the tools needed to address the complexity of this evolving field.