OP White Papers - random

1. Assessing A Targeted Molecular Method Against Traditional In Vitro Testing For Adventitious Virus Detection 10/3/2024

   Discover a CHO AOF panel that provides rapid detection of relevant adventitious viral contaminants in bulk harvest material, and explore data showing equivalent sensitivity to the in vitro assay.

2. Engineering Reliability In Cell Therapy Manufacturing 2/3/2026

   A cell therapy manufacturing model built on precision planning, digital execution, lifecycle‑ready CMC systems, and transparent collaboration to achieve high reliability and reduce variability across programs.

3. Transformative Innovation: Advancing Drug Development Using In Silico Modeling 3/4/2026

   Explore how predictive modeling and in silico strategies can turn complex data into actionable insights that accelerate drug development and reduce risk across the development lifecycle.

4. Molecular Properties Of PROTACs And The Relationship To Formulation Design 3/4/2025

   Here, we conduct a comprehensive analysis of diverse PROTAC (Proteolysis Targeting Chimeras) structures, evaluating their calculated physicochemical properties to identify key trends.

5. Application Of Plant And Process Models 1/22/2025

   Explore innovative process and facility models that optimize efficiency, sustainability, and cost-effectiveness in biopharmaceutical manufacturing.

6. Human Skin Explant Model For The Investigation Of Topical Therapeutics 8/4/2025

   Learn more about an ex vivo cultured human skin explant model in which pathological tissue integrity, barrier function, and metabolic stability have been characterized over time.

7. Manufacturing Of Cytotoxic And Non-Cytotoxic Drugs In A Multiproduct Facility 10/16/2024

   The experience and expertise of the CMO is crucial to avoid the risk of cross-contamination of the drug product, as failures or weaknesses in this process can pose risk to the end-user.

8. Advances In High-Concentration Protein Formulation Development 11/25/2025

   High-concentration protein formulations improve patient convenience but face challenges like viscosity, aggregation, and surfactant degradation. Innovative strategies optimize stability, scalability, and quality for advanced biologics development.

9. The Benefits Of Incorporating Lean Methodologies Into Project Management 8/20/2024

   Delve into the core principles of lean project management and explore how these principles can be integrated with traditional methods to enhance project outcomes.

10. Optimizing Safety Measures For rAAV Therapies 10/11/2024

    Explore common process-related impurities found in recombinant Adeno-Associated Virus (rAAV) vectors and the analytical testing methods used for these residuals.