Milliporesigma Brochures

  1. Optimization Of Benzonase® Endonuclease Use In Virus Purification

    The use of Benzonase® endonuclease additionally increases the yield in virus purification, protects the downstream chromatography and filter devices from fouling and reduces feed stream viscosity. In this document we will provide you guidance on how to plan and set up a Design of Experiments (DoE) optimization experiment of Benzonase® endonuclease in your viral gene therapy process.

  2. CHO Cell Culture Media And Feeds - Selection Guide

    Explore a range of off-the-shelf solutions created to support all your cell line development needs and CHO production processes.

  3. Gene Therapy Capabilities For AAV And Lentivirus Production

    Explore all of our gene therapy solutions for AAV and Lentivirus manufacturing based on 30+ years of experience to help bring your therapy to life. 

  4. Comprehensive Solutions For Your Vaccine Platforms

    Vaccine production, from process development to full-scale GMP-manufacturing, must be efficient, safe, and cost-effective. Learn how our global capabilities can help you achieve these goals for all your modalities/platforms.

  5. Analytical Development & Characterization For AAV

    Our assay packages and phase-appropriate assay development and validation capabilities provide the product and process knowledge you need to develop a QTPP and identify the CQAs for your therapy.

  6. Adeno-Associated Virus (AAV) Biosafety Testing & Characterization Services

    Biosafety testing and characterization for new products are essential as they emerge for clinical study. Both measures will help mitigate safety concerns and confirm product quality before these therapies are administered to patients. Our BioReliance® AAV testing services give you the confidence to get your products to market quickly and safely.

  7. Cellvento® 4CHO-X Brochure

    The new Cellvento® 4CHO-X Expansion Medium supports cell expansion including N-1 perfusion for Chinese Hamster Ovary (CHO) cell lines.

  8. Medium For Producing High AAV Titers In Multiple HEK293 Cell Lines

    Discover a chemically defined medium optimized for AAV production that has been streamlined and cell culture media components incorporated to increase media stability and reduce protein oxidation.

  9. A Transfection-Based Solution With Proven Performance At Scale

    The VirusExpress® 293 AAV Production Platform offers a transfection-based solution using a suspension-adapted cell line, which is GMP banked and characterized chemically defined medium, and a process with proven performance at a clinically relevant scale.