Cell and Gene Outsourcing

  1. Optimization-By-Design — A Critical Factor In Viral Vector Scale Up 12/14/2023

    Learn how leveraging the expertise and capabilities of an experienced partner is a key factor in optimizing AAV processes using Design of Experiment (DoE), thereby reducing variability and risk.

  2. Meet The Experts: Part 1 - Process Analytical Technology (PAT) 5/1/2023

    Watch part 1 of this 4-part interview series to learn about process analytical technology (PAT) from expert Stacy Shollenberger.

  3. How MilliporeSigma Promotes Quality And Risk Reduction 10/20/2021

    Learn how MilliporeSigma’s new facility was built with quality and risk reduction at the top of mind and its experts have the experience to support large-scale programs through commercialization.

  4. Purity As A Priority: Optimizing Safety Measures For rAAV Therapies 2/11/2025

    Watch to learn how rAAV vectors in gene therapy are addressing manufacturing impurities, risks to patient safety, and analytical methods for detection while aiding sponsors in regulatory compliance.

  5. Viral Safety Of Biologics: What's Changing With The ICH Q5A Revision? 6/13/2022

    ICH Q5A is currently being revised to address recent scientific advancements. We'll discuss the expected changes and potential impact on viral safety strategies.

  6. How To Boost AAV Titer With Feed Supplementation In Both HEK293 And Sf-9 Platforms 11/25/2024

    Explore how optimizing post-transfection or post-infection feeding in HEK293 and Sf-9 cells significantly boosts AAV titers, enhancing production efficiency for gene therapy applications.

  7. Evaluating Viral Clearance For Continuous Processes 10/18/2020

    Is viral clearance a hurdle to implementing continuous processing? Here we share virus spiking alternatives that may pave the way for evaluating viral clearance by chromatography steps.

  8. How To Bring Your LNP Formulation To Clinical/Commercial Manufacturing

    Gain valuable insights into key considerations when selecting lipid excipients for LNP formulations and the process development steps necessary to advance them to GMP manufacturing and clinical trials.

  9. Empowering Your Plasmid DNA Workflow 3/4/2025

    Unlock the full potential of your pDNA purification with advanced chromatography solutions and resins that tackle high viscosity and impurities to ensure superior quality and yield.

  10. Meet The Experts: Part 4 – Applications And Use Of Raman In Bioprocessing 5/1/2023

    Watch the fourth and final interview of this 4-part series to learn about Raman applications in bioprocessing from expert Célia Sanchez.