ABOUT SYNGENE INTERNATIONAL
Syngene International Ltd. is a publicly listed, global CRDMO headquartered in Bengaluru, India, delivering integrated discovery, development, and manufacturing services to pharmaceutical and biotech innovators. With 6,500+ employees including ~5,000 scientists and cGMP manufacturing facilities across the U.S. and India, Syngene supports 400+ active clients globally through longterm, strategic partnerships.
End-To-End CRDMO Capabilities
Syngene provides end-to-end CRDMO services across small molecules, biologics, and advanced modalities. Its capabilities span discovery through commercial manufacturing, supported by dedicated R&D centers including its flagship Bristol Myers Squibb (BMS) dedicated center. The company has built strong platforms in TIDES (peptides and oligonucleotides) and XDCs, alongside a robust small molecule and biologics backbone. Manufacturing scale includes ~50 kL biologics capacity and ~135 kL small molecule capacity, complemented by commercial fill/finish capabilities up to ~1 million via ls/da y. Integrated platforms and automation enable seamless transition from discovery to development and commercial supply.
Quality, Scale, and Sustainability
Syngene operates globally accredited, cGMP-compliant facilities with approvals from US FDA, EMA and other regulators, supporting programs for regulated markets. The company has enabled innovation through 400+ pa tents with partners and continues to scale its global delivery model. Its ESG performance is a key differentiator, with >80% renewable energy usage, zero waste to landfill, and science-based emissions reduction targets. Backed by strong governance, global partnerships, and a growing international footprint, Syngene is a trusted partner in advancing therapies from lab to market.
LARGE MOLECULE RESEARCH & PERSPECTIVES
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Modernize quality control by integrating automated workflows, digital records, and advanced training. Eliminating paper protects data integrity and accelerates regulatory timelines.
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Multi-continent manufacturing networks minimize supply chain risk. Relying on site alignment, robust tech transfer, and unified quality standards ensures a flexible and resilient supply chain.
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Biologics outsourcing is shifting to strategic partnerships focused on modality expertise, regulatory excellence, and integrated end-to-end capabilities.
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Supply chain visibility and proactive risk strategies are vital to navigate new federal biotech restrictions and protect drug development pipelines.
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Antibody-drug conjugates are reshaping cancer treatment. Learn how monoclonal antibody targeting, linker design, and next-gen payloads are defining the future of precision oncology.
SMALL MOLECULE RESEARCH & PERSPECTIVES
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Geopolitical shifts require production diversification. Balancing regional proximity with cost-effective manufacturing hubs ensures uninterrupted supply and insulates critical drug pipelines.
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Successful oral solid dosages must solve real-world patient challenges. Focus on physiology-driven formulation to mitigate variability, manage food effects, and minimize pill burden.
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Long-acting injectables improve adherence via sustained release, while advanced technologies, integrated development, and modeling address formulation, manufacturing, and regulatory challenges.
CONTACT INFORMATION
Syngene International Ltd.
Biocon SEZ, Biocon Park, Plot.No.2 & 3, Bommasandra Indst Area IV Phase, Jigani Link Road
Bangalore, Karnataka, 560100
INDIA
Contact: Ishwarya S. Associate Director: Integrated Marketing, Ishwarya.S1@syngeneintl.com +91 8105521687
U.S. FACILITIES
Syngene International Ltd.
5901 E Lombard St.
Baltimore, MD 21224
LARGE MOLECULE BROCHURES
SMALL MOLECULE BROCHURES
LARGE MOLECULE SUCCESS STORIES
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Transposon-based cell line development cuts timelines by 10 weeks and hits titers of 4.8 g/L in 17 days. See how SynWeave delivers measurable biologics manufacturing gains.
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Producing bispecific antibodies at scale is notoriously difficult. See how Syngene achieved a 3X yield increase and 98.5% purity for Hinge Bio's GEM-DIMER™ platform in just seven months.
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N-1 perfusion technology increased antibody titers 1.5–4.5x over conventional fed-batch methods. See how high seed density and media blending cut costs and maximize suite utilization.
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N-1 perfusion improves antibody production by increasing cell density, optimizing media and conditions, boosting yields up to 4.5× while maintaining quality and reducing manufacturing time and costs.
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A platform-based upstream strategy increased monoclonal antibody titers fourfold, improving yield, efficiency, and scalability via optimized clones, process design, and rapid scale-up.
SMALL MOLECULE SUCCESS STORIES
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Gain insight into a first-time-right process that improved yield and scalability, advancing a vascular calcification inhibitor from lab scale to tox and GMP manufacturing for clinical development.
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Looking to bring an innovative animal health product to market? See how we delivered end-to-end formulation development and rapid clinical supply manufacturing for complex multi-API products.
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Process optimization delivered a scalable, cost-effective synthesis, increasing yield and reducing waste, solvents, and costs while enabling rapid transition from lab to cGMP manufacturing.
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Outsourcing stability testing improved efficiency, reduced costs, and enhanced scalability, enabling robust lifecycle support, regulatory compliance, and optimized resource utilization across programs.
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Process innovation reduced synthesis steps, increased yield, and improved chiral purity, enabling faster, scalable manufacturing of a pancreatic cancer therapy for clinical and commercial development.