Newsletter | October 16, 2026

10.16.26 -- The Case Of The Half Pill: AI As Outsourcing Detective

SPONSOR

Spray Dried Biologics For Injectable Dosage Forms

Spray drying is transforming biologic drug delivery by converting sensitive biologics into stable dry powders. The technology also enables advanced formulations, including ultra-high concentration and encapsulated biologics for subcutaneous administration. Read how these capabilities support greater patient convenience through self-administration while maintaining therapeutic performance. Read more.

INDUSTRY INSIGHTS

The Future Of Sustainable Amorphous Dispersion Development

Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.

An Integrated Model For Faster PFS Development

Discover how integrated, end-to-end development for prefilled syringes can streamline timelines, enhance patient-centric delivery, and scale efficiently from early development to global launch.

Peptide Building Blocks: Frequently Asked Questions

High-quality starting materials improve yield, reduce synthesis risk, and support reliable manufacturing across therapeutic development.

FEATURED EDITORIAL

The Case Of The Half Pill: AI As Outsourcing Detective

A number of patients report receiving half a pill in a blister pack of their prescribed medicine. The initial sponsor reaction is to place the problem at an external partner’s production or packaging line. But overall responsibility lies with the sponsor, and the true extent of the problem is hard to detect. Enter AI. Experienced pharma quality expert Damiano Dragone believes AI combined with professionals throughout the supply chain can join in a new “logic and creativity" to improve our industry on behalf of patients.

Are You Falling Behind On Intelligent Pharmaceutical Manufacturing?

With a focus on small molecule drug product manufacture, let's take a closer look at the efficiencies gained through closed-loop control, PAT, digital twins, and more.

INDUSTRY INSIGHTS CONTINUED

Organometallic Chemistry In API Manufacturing

Organometallic chemistry enables complex bond formation for pharmaceutical synthesis. Specialized cryogenic systems, closed handling, thermal control, and safety frameworks support reliable scale-up.

Delivering API-In-Capsule For Potent, Low-Flow Compounds

See how an automated capsule-filling approach addressed poor-flow APIs, improved operator safety, and supported fast scale-up for clinical supply needs.

Enhancing Bioavailability And Therapeutic Efficacy

Assimilate how lipid-based softgel formulations can enhance drug absorption, improve bioavailability, and advance drug delivery across a range of therapeutic applications.

The Crucial Role Of Project Managers In Selecting A CDMO Partner

Leverage the expertise of experienced project managers to select the right CDMO partner, mitigate risk, and drive your pharmaceutical program toward faster, more successful outcomes.

The 5 Key Risks Of Failing To Select The Right CDMO Partner

For complex projects involving oral solid dosage (OSD) and sterile drug products, selecting the ideal CDMO can play a pivotal role in determining the success of a drug candidate.

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Bioavailability & Solubility | Nov. 10, 2026, 11:00 AM ET

This session explores formulation strategies for overcoming bioavailability and solubility challenges in drug development. CDMOs will discuss how they evaluate difficult molecules, apply specialized technologies and analytical expertise, and develop formulations that improve drug performance. Attendees will gain insights into early development decisions, scalable manufacturing approaches, and selecting outsourcing partners that can help advance promising candidates toward commercial success. Learn more.

SOLUTIONS

Human ADME Studies: Human Metabolism Data For Regulatory Submission

Hydrocortisone API Catalogue At Curia

Advancing Analgesic Development With Validated Pain Models

OUTSOURCED PHARMA CAPABILITIES UPDATE

Find Your New CDMO At Outsourced Pharma Capabilities Update

CDMOs in biologics, cell and gene, and small molecule share their capabilities and available capabilities. See for yourself why this virtual event has become a wildly popular resource to identify options for your development and manufacturing needs.

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