Sustainability In Small Molecule API Manufacturing

Active pharmaceutical ingredient (API) manufacturing accounts for roughly a quarter of the pharmaceutical industry’s greenhouse gas emissions, making it a key area for sustainability innovation. This white paper explores how applying green chemistry principles, such as atom economy, safer solvents, and energy efficiency, can transform small molecule API production. It outlines a three-pillar approach: education and training, smart synthesis design, and measurement and optimization. Tools like DOZN™ and GreenSpeed enable data-driven decision-making and real-time sustainability assessments. Through detailed case studies, discover how process redesign, such as eliminating chromatography steps or adopting continuous flow manufacturing, can dramatically reduce waste, solvent use, and carbon footprint while improving yield and cost-efficiency. For organizations seeking actionable strategies to meet decarbonization goals, this resource offers practical, scalable solutions rooted in scientific rigor.

Explore the full white paper to see how sustainability and performance can go hand in hand.