E-Book | June 10, 2025

Spray Drying Nanosuspensions: A Novel Approach For Improved Bioavailability In Solid Dosage Forms

Source: Altasciences
Pharmaceutical Tablets GettyImages-610221624

More than 70% of newly developed chemical entities suffer from low aqueous solubility — a critical limitation that directly impacts a drug’s ability to dissolve within the body. Since dissolution is a prerequisite for absorption, poor solubility can significantly reduce a compound’s bioavailability and compromise its therapeutic potential.

At the forefront of pharmaceutical innovation, our team leverages advanced formulation development strategies to address these solubility challenges head-on. With industry-leading expertise in nanomilling and state-of-the-art spray drying capabilities, we deliver robust, scalable solutions for even the most complex active pharmaceutical ingredients (APIs).

By combining nanomilling and spray drying technologies, we offer an integrated approach that enhances dissolution rates, improves bioavailability, and ultimately increases therapeutic efficacy. This synergy between particle size reduction and amorphous solid dispersion opens the door to new possibilities in drug delivery, enabling the successful development of compounds once considered too challenging to advance.

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