Quadrant 2®: Predictive Platform For Solubility And Bioavailability Enhancement

Solubility & bioavailability enhancement strategy: save time & costs

Many of today’s drug development candidates have low solubility and bioavailability challenges, which need to be resolved before clinical studies can be performed. Therefore, early formulation development would typically involve several trial-and-error experiments and screening studies to identify an enabling technology that works and typically takes 14 to 19 months to complete.

Quadrant 2^® helps in early formulation development by insilico predictions of formulations via computational modeling. It analyses your compound’s specific molecular  structure and chemical characteristics, in combination with your unique target product profile. The Quadrant 2^® platform consists of proprietary algorithms that incorporate a variety of different computational methods including Quantum mechanics, Molecular Dynamics, QSAR, ADMET, statistical analysis and internally developed models. Using your compound’s individualized data, this program can predict the most optimal solubility enhancement technology and excipient combination that are most likely to succeed.