Article | November 5, 2021

Patient-Centric Dosage Forms: A Viable Solution To Non-Adherence

By Srinivasan Shanmugam, PhD, Senior Director, Pharmaceutical Sciences, Business Support and New Technologies, Adare Pharma Solutions

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One of the biggest challenges facing pharmaceutical companies is patient acceptance and adherence to prescribed therapeutic dosing regimens; particularly special patient populations (paediatrics and geriatrics) and patients suffering from chronic and multi-morbid diseases. Beyond the burden imposed on the healthcare system (including patients and caregivers), non-adherence often undermines the safety and efficacy of the therapeutics, leading to poor therapeutic outcomes including increased morbidity and mortality. Consequently, addressing dosing regimen non-adherence is of paramount interest.

Therapy-related factors (eg, poor taste of the medication, frequent dosing, number of medications, and difficulty of application) and patient-related factors (eg, swallowing and motor impairment) can efficiently be addressed via patient-centric dosage forms. Better adherence can often result by considering therapy- and patient-related factors during the design and development of patient-centric dosage forms.

Unfortunately, the lack of patient-centric formulations tailored for specific population groups and/or specific disease conditions suggests a failure to properly weigh such factors during dosage form development.

Adare Pharma Solutions (Adare), a technology-driven company whose purpose is “to improve life for patients through technologically enhanced formulations,” understands the significance of patient-centric dosage forms and their role in improving acceptance and adherence.

To learn more about the options for patient-centric dosage forms, access the article.

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