Newsletter | March 17, 2026

03.17.26 -- Not So Fast Into The Night: Your Outsourcing Needs A Pause

INDUSTRY INSIGHTS

The Next Frontier In mRNA

Explore constructing a modular RNA-LNP GMP facility using an integrated, flexible process train in a turnkey modular environment to scale RNA-LNP therapies.

How To Design And Evaluate Bispecific Antibodies (BsAbs)?

Bispecific antibodies combine two antigen-binding sites to enhance efficacy and safety. Their design requires structural strategy, MOA-based evaluation, and screening for optimal therapeutic performance.

Engineering Rep-Cap Plasmids To Enhance AAV Manufacturability, Potency

Discover how our engineered Rep-Cap plasmids dramatically enhance AAV vector yield, quality, and scalability, offering a powerful, next-generation solution to overcome manufacturing challenges.

FEATURED EDITORIAL

Not So Fast Into The Night: Your Outsourcing Needs A Pause

Barreling through the initial months of the year? Here’s a suggestion from Chief Editor Louis Garguilo to pump the breaks for a bit. Take one more glance in the rearview mirror to assess your current progress, reconfirm your pathway is your intended one. An outsourcing pause might pay off handsomely this year, and that’s because a lot happened last year on the supply-chain front. You made plans and formed expectations based on those trends and experiences. Are you currently abiding by those analyses?

To Fight Cancer, Gene Editing Needs To Solve Its Delivery Problem

The choice of delivery dictates the complexity of manufacturing, which in turn determines the eventual cost and accessibility of the therapy.

INDUSTRY INSIGHTS CONTINUED

Partnering For Success In Oncolytic Virus Development

Learn how to navigate decision-making at critical steps and find solutions to key challenges in process development and scale-up to expedite oncolytic virus programs.

Why Flexible, Collaborative Distribution Partners Matter For CGTs

Assimilate how collaborative distribution models manage reimbursement hurdles and complex delivery requirements to ensure patient access and long-term commercial success.

Viral Vectors: The Backbone Of Cell And Gene Therapy

Viral vectors are the indispensable backbone of genetic medicine. View the fundamental trade-offs and manufacturing strategies for large-scale production of AAV and lentiviral delivery systems.

New Technology Platforms Being Developed

New tools and technologies are reshaping drug development, enabling faster discovery, better scalability, and greater precision across biologics and advanced therapies.

Defining The Required CQAs For mRNA/LNP Product Development

Uncover how early identification of CQAs can streamline mRNA drug product development, reduce risk, and align with evolving regulatory expectations.

Navigating Lentiviral Therapy Commercialization

Review the results obtained for our proprietary HEK293T 2G7 suspension cell line for LVV production by transient transfection in serum-free, chemically-defined, and animal component-free media.

Time: A Crucial Factor In Therapeutics Development

Accelerate your mRNA development and strengthen your response to emerging health threats with next-generation, cell-free DNA template solutions designed for speed, quality, and reliability.

Revolutionizing Gene Therapy Manufacturing

By integrating perfusion into upstream manufacturing, see how this approach has achieved up to a fivefold increase in productivity, delivering titers that significantly exceed current industry benchmarks.

SOLUTIONS

A Faster, More Sensitive Approach To Virus Detection

Examine a faster, more sensitive approach to rodent virus detection that offers a targeted NGS workflow to help uncover contaminants traditional assays may miss.

One-Step Large Knock-In Technology

Identify a one-step gene-editing method designed to streamline the integration of large DNA sequences into cells. This technology increases editing, reduces timelines, and improves the reliability of cell lines.

Give Your Gene Therapy The Kickstart It Deserves

Optimize AAV gene therapy development with construct and process enhancements, boosting titers, potency, and scalability for cost-efficient manufacturing and accelerated timelines.

OUTSOURCED PHARMA CAPABILITIES UPDATE

Find Your New CDMO At Outsourced Pharma Capabilities Update

CDMOs in biologics, cell and gene, and small molecule share their capabilities and available capabilities. See for yourself why this virtual event has become a wildly popular resource to identify options for your development and manufacturing needs.

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