White Paper: Nasal Delivery Of Spray Dried Biologics: Opportunities And Challenges

By Dr. Richard Johnson, Chief Scientific Officer

Interest in the nasal delivery of biologics has surged due to the efficacy of spray drying as the preferred method for creating stable dry powder products. Dr. Richard Johnson, Chief Scientific Officer at Upperton Pharma Solutions, emphasizes the advantages of spray-dried nasal formulations, which provide excellent stability, targeted nasal deposition, and enhanced permeation, all while offering a reliable pathway to commercial-scale manufacturing.

Key topics include the nasal anatomy and potential delivery targets, barriers to effective delivery and pathways into the body, the use of spray drying to produce particle formulations for successful nasal delivery, and the testing of spray-dried nasal formulations containing biologics.