Application Note

Multivariate Inter-Stage Batch Profile Monitoring And Future State Estimation For Efficient Control And Planning Of Manufacturing Operations

By Anshuman Bansal, Head of Process Analytics, BioContinuumâ„¢ Platform

As process engineers supporting multistage biologics manufacturing, we must continually monitor the health of our process. As a batch progresses from one stage to the next, we have to scrutinize hundreds of individual process parameters to understand the current process state. How much quicker and easier would it be if we could know the process’s health by looking at a single metric rather than checking hundreds of parameters?

With Bio4C ProcessPad™, users can now create a single batch profile chart with monitoring ranges derived from PCA models created using batches which have the desired parameter values at the various stages of the manufacturing process.

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