Case Study

Microcaps Exceeds Stringent Requirements Beyond Taste Masking

By Luigi Boltri, Senior Director, Pharmaceutical Sciences, Business Support & New Technologies, Adare Pharma Solutions

Improving Flow Characteristics for APIs and Diluents in Pharmaceutical Formulations

The Challenge

A particularly bitter pediatric macrolide in powder form was brought to Adare for needs beyond just taste masking. The API also needed:

  • Fast release due to a narrow absorption window
  • A smooth syrup mouthfeel acceptable to children and infants
  • Over seven days of taste masking after suspension
  • Drug loading suitable for its high dose

By pairing the API with Adare’s industry leading Microcaps technology, all requirements were met and, in most cases, exceeded.


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