Masking Bitter Drug Taste In Pediatric Formulations With Microcaps

The powder formulation is stable in home environments, easy to administer and has flexible dosing variations for children over two and adults for whom a solid dosage form is not appropriate.

The Challenge

Adare Pharma Solutions was asked to create a taste masked, convenient dosage formulation of a very bitter API for patients two-years old and older undergoing treatment of HIV infection. As the drug would be administered in patient home settings, sub-optimal distribution and storage conditions, would need to be also considered as well as flexible dose requirements due to patient to patient weight and age variations.