How To Prevent Protein Aggregation Through Stabilizers And Surfactants

In this webinar, you will learn:

• About mechanisms involved in the formation of protein particles
• Why different classes of excipients are required to prevent protein aggregation
• About our novel surfactants/stabilizers and their capability to overcome challenges associated with protein instability

Detailed description:

Aggregation of therapeutic proteins can occur during all steps of drug product manufacturing and handling. One option to efficiently prevent protein aggregation in solution is the application of excipients. Depending on the underlying mechanism of protein aggregation, different classes of excipients such as stabilizers and surfactants are required to stabilize the protein. Stabilizers enhance protein stability in the bulk whereas surfactants efficiently prevent agitation- and surface-induced protein aggregation.

This webinar will provide a comprehensive overview of protein aggregation, underlying mechanisms and stabilization techniques using (novel) excipients in parenteral formulations.