How To Accurately Enhance Drug Solubility And Bioavailability

Nanomilling is an advanced manufacturing technique that tackles the common challenge of poor water solubility and limited bioavailability in drug development. By reducing particle sizes to the nanometer scale, nanomilling dramatically increases the surface area of active pharmaceutical ingredients (APIs), thereby enhancing their dissolution rates and absorption.

Beyond improving solubility, nanomilling provides a range of benefits, including lower dose volumes for parenteral administration, the elimination of harsh solvents, and the ability to create inhalable formulations optimized for deep lung delivery. Additional advantages include reduced fed/fasted variability, faster therapeutic onset, and the potential for seamless integration into continuous manufacturing processes, making it a versatile solution for modern pharmaceutical applications.

Discover how nanomilling, a game-changing technique that tackles poor solubility and bioavailability in drug development, can optimize your drug’s formulation by downloading the infographic below.