Decoding A T Cell Fingerprint: All You Need To Know About TCR Sequencing
T-cell receptor (TCR) sequencing holds transformative potential in advancing our understanding of the immune system. TCRs are crucial for recognizing and responding to diverse antigens, with an estimated diversity ranging from 10¹⁵ to 10¹⁹ unique TCR rearrangements. This vast diversity, known as the T-cell repertoire, is essential in fields like oncology, immuno-oncology, cell and gene therapy, and vaccine development.
This white paper delves into how next-generation sequencing (NGS) technology enables the precise decoding of these immune repertoires, offering valuable insights for both preclinical and clinical applications. Through detailed case studies and technical explanations, learn how TCR sequencing can improve patient stratification, treatment monitoring, and the development of novel therapeutics.
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