Ask Better, Move Faster: Questions That Will Accelerate The Speed Of Your Program To Clinical

By Ranjit Verma, Associate Director of Chemical Development

Advancing a new chemical entity into the clinic requires more than technical expertise. It depends on asking the right questions at the right time. Early development programs often face pressure to move quickly, but overlooking critical decisions around manufacturing, scalability, safety, sourcing, or regulatory readiness can create costly delays later in the process.

A successful path to the clinic starts with clearly defining program goals and distinguishing between essential requirements and desirable future improvements. Teams must also evaluate whether current synthetic routes can support larger production volumes, identify potential safety and containment challenges, and assess supply chain risks before they become obstacles. Just as importantly, planning for analytical, regulatory, and intellectual property needs early can help avoid surprises as development progresses.

By taking a strategic approach to decision-making, organizations can reduce uncertainty, allocate resources more effectively, and maintain momentum through key development milestones. Discover the questions that can help development teams make smarter choices, minimize risk, and accelerate progress toward clinical trials.