A Word With Susan Li, Peptide Chief Scientist, Asymchem

Rapid advancements in TIDES development are reshaping expectations for scalability, quality, and sustainability — areas where forward‑looking manufacturing strategies can make a measurable difference. This conversation with peptide expert Susan Li highlights how next‑generation process design, digital integration, and green chemistry principles are converging to build more resilient and efficient pathways from early development through commercialization. Readers gain a clear view into how technologies like TAG‑assisted liquid‑phase synthesis, continuous purification, and enzymatic ligation reduce impurities, increase yield, and alleviate long‑standing bottlenecks found in traditional solid‑phase approaches. Equally valuable is the exploration of digital tools such as PAT and AI‑enabled data feedback loops, which enhance real‑time control and accelerate decision‑making. Li also sheds light on how integrated supply chain strategies and proprietary technologies contribute to stronger reliability across the molecule lifecycle.

This interview offers insight for teams navigating rising complexity in peptide and oligonucleotide programs, highlighting practical methods to streamline development, strengthen sustainability, and build platforms prepared for future demand. Explore the full interview for a deeper look at the innovations shaping modern TIDES manufacturing.