A Scalable Solution For Solubility Challenges

With over 70% to 80% of small molecule products in today's drug development pipeline characterized by poor solubility, thanks to updated screening methods and bioavailability enhancements, formulating such drugs as tablets poses a significant challenge.

To address this, formulation scientists have turned to two-piece, liquid-filled hard-shell capsules as a viable solution. Beyond their primary advantage of accommodating poorly soluble compounds, these capsules offer additional attractive features. They facilitate rapid development and testing, expediting the transition from research and development to clinical phases. The flexibility to easily adjust the amount of active ingredient allows the manufacturing of different dosages with the same specifications. Furthermore, when it comes to market readiness, the scale-up of the manufacturing process for commercialization is a straightforward process.

Explore the potential of liquid-filled hard-shell capsules to transform formulation challenges into simple solutions and the benefits they offer patients through increased bioavailability and sustained release drug delivery.